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Table 4 Multivariable logistic regression model for hospital mortality in COVID-19 patients (n = 7780, death = 251, 3.2%)

From: Impact of coronavirus disease-2019 on chronic respiratory disease in South Korea: an NHIS COVID-19 database cohort study

Variable

Multivariable model

P-value

OR (95% CI)

Chronic respiratory diseases (model 1)

1.19 (0.86, 1.64)

0.299

Chronic respiratory diseases: sensitivity analyses (model 2)

  

 COPD

1.56 (1.06, 2.2)

0.024

 Asthma

1.03 (0.76, 1.41)

0.834

 Interstitial lung disease

1.83 (0.74, 4.55)

0.193

 Lung cancer

1.82 (0.80, 4.14)

0.154

 Lung disease d/t external agent

3.54 (1.70, 7.38)

 < 0.001

 Obstructive sleep apnea

0.47 (0.06, 3.94)

0.486

 Tuberculosis of lung

1.65 (0.48, 5.64)

0.423

Age, 10 year increase

2.85 (2.40, 3.38)

 < 0.001

Income level

  

 Q1 (Lowest)

1

 

 Q2

0.96 (0.59, 1.57)

0.882

 Q3

1.08 (0.70, 1.65)

0.739

 Q4 (Highest)

0.89 (0.652, 1.30)

0.554

 Unknown

0.67 (0.18, 2.54)

0.560

Sex, male

2.12 (1.55, 2.88)

 < 0.001

Residence

  

 Seoul

1

 

 Gyeonggi-do

2.26 (0.75, 6.86)

0.148

 Daegu

2.60 (0.74, 9.16)

0.136

 Gyeongsangbuk-do

2.40 (0.77, 7.49)

0.133

 Other area

1.69 (0.50, 5.72)

0.401

Underlying disability

1.33 (0.94, 1.89)

0.109

Charlson comorbidity index, model 2

1.80 (1.32, 2.44)

 < 0.001

 Hypertension

1.36 (0.89, 2.06)

0.153

 DM without chronic complication

1.87 (1.35, 2.59)

 < 0.001

 DM with chronic complication

1.61 (1.06, 2.45)

0.027

 Peripheral vascular disease

1.19 (0.81, 1.76)

0.76

 Renal disease

1.47 (0.87, 2.47)

0.148

 Rheumatic disease

0.58 (0.30, 1.12)

0.107

 Dementia

1.61 (1.11, 2.32)

0.011

 Peptic ulcer disease

1.04 (0.73, 1.49)

0.818

 Hemiplegia or paraplegia

1.92 (1.03, 3.59)

0.040

 Moderate or severe liver disease

5.12 (1.32, 19.90)

0.018

 Mild liver disease

0.80 (0.58, 1.10)

0.170

 Cerebrovascular disease

0.57 (0.38, 0.87)

0.009

 Congestive heart failure

1.91 (1.38, 2.66)

 < 0.001

 Myocardial infarction

0.79 (0.47, 1.33)

0.374

 Malignancy

1.07 (0.78, 1.46)

0.694

 Metastatic solid tumor

1.37 (0.85, 2.19)

0.192

 AIDS/HIV

1.43 (0.11, 19.37)

0.788

  1. AUC of the multivariable models: 0.83 (95% CI 0.82 to 0.83)
  2. OR, odds ratio; CI, confidence interval; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; AIDS, acquired immune deficiency syndrome; HIV, Human Immunodeficiency Virus