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Table 4 Multivariable logistic regression model for hospital mortality in COVID-19 patients (n = 7780, death = 251, 3.2%)

From: Impact of coronavirus disease-2019 on chronic respiratory disease in South Korea: an NHIS COVID-19 database cohort study

Variable Multivariable model P-value
OR (95% CI)
Chronic respiratory diseases (model 1) 1.19 (0.86, 1.64) 0.299
Chronic respiratory diseases: sensitivity analyses (model 2)   
 COPD 1.56 (1.06, 2.2) 0.024
 Asthma 1.03 (0.76, 1.41) 0.834
 Interstitial lung disease 1.83 (0.74, 4.55) 0.193
 Lung cancer 1.82 (0.80, 4.14) 0.154
 Lung disease d/t external agent 3.54 (1.70, 7.38)  < 0.001
 Obstructive sleep apnea 0.47 (0.06, 3.94) 0.486
 Tuberculosis of lung 1.65 (0.48, 5.64) 0.423
Age, 10 year increase 2.85 (2.40, 3.38)  < 0.001
Income level   
 Q1 (Lowest) 1  
 Q2 0.96 (0.59, 1.57) 0.882
 Q3 1.08 (0.70, 1.65) 0.739
 Q4 (Highest) 0.89 (0.652, 1.30) 0.554
 Unknown 0.67 (0.18, 2.54) 0.560
Sex, male 2.12 (1.55, 2.88)  < 0.001
Residence   
 Seoul 1  
 Gyeonggi-do 2.26 (0.75, 6.86) 0.148
 Daegu 2.60 (0.74, 9.16) 0.136
 Gyeongsangbuk-do 2.40 (0.77, 7.49) 0.133
 Other area 1.69 (0.50, 5.72) 0.401
Underlying disability 1.33 (0.94, 1.89) 0.109
Charlson comorbidity index, model 2 1.80 (1.32, 2.44)  < 0.001
 Hypertension 1.36 (0.89, 2.06) 0.153
 DM without chronic complication 1.87 (1.35, 2.59)  < 0.001
 DM with chronic complication 1.61 (1.06, 2.45) 0.027
 Peripheral vascular disease 1.19 (0.81, 1.76) 0.76
 Renal disease 1.47 (0.87, 2.47) 0.148
 Rheumatic disease 0.58 (0.30, 1.12) 0.107
 Dementia 1.61 (1.11, 2.32) 0.011
 Peptic ulcer disease 1.04 (0.73, 1.49) 0.818
 Hemiplegia or paraplegia 1.92 (1.03, 3.59) 0.040
 Moderate or severe liver disease 5.12 (1.32, 19.90) 0.018
 Mild liver disease 0.80 (0.58, 1.10) 0.170
 Cerebrovascular disease 0.57 (0.38, 0.87) 0.009
 Congestive heart failure 1.91 (1.38, 2.66)  < 0.001
 Myocardial infarction 0.79 (0.47, 1.33) 0.374
 Malignancy 1.07 (0.78, 1.46) 0.694
 Metastatic solid tumor 1.37 (0.85, 2.19) 0.192
 AIDS/HIV 1.43 (0.11, 19.37) 0.788
  1. AUC of the multivariable models: 0.83 (95% CI 0.82 to 0.83)
  2. OR, odds ratio; CI, confidence interval; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; AIDS, acquired immune deficiency syndrome; HIV, Human Immunodeficiency Virus