Total (n = 192) | High ADA (≥40 IU/L) (n = 156) | Low ADA (< 40 IU/L) (n = 36) | p-value | |
---|---|---|---|---|
Age (years) | 64.5 (±20.5) | 62.0 (±20.7) | 75.3 (±15.4) | < 0.001 |
Sex (% male) | 130 (67.7%) | 110 (70.5%) | 20 (55.6%) | 0.084 |
Smoking status | 0.322 | |||
Never smoker | 103 (53.6%) | 83 (53.2%) | 20 (55.6%) | |
Current smoker | 43 (22.4%) | 38 (24.4%) | 5 (13.9%) | |
Former smoker | 46 (24.0%) | 35 (22.4%) | 11 (30.6%) | |
DM | 41 (21.4%) | 33 (21.2%) | 8 (22.2%) | 0.888 |
HTN | 81 (42.2%) | 60 (38.5%) | 21 (58.3%) | 0.030 |
History of TB | 17 (8.9%) | 14 (9.0%) | 3 (8.3%) | 0.903 |
Pleural fluid analyses | ||||
WBC (/μL) | 4,141 (±15,970) | 4362 (±17,371) | 3,168 (±7,229) | 0.708 |
PMNs (%) | 25.4 (±31.2) | 23.7 (±29.7) | 33.2 (±36.6) | 0.153 |
Lymphocyte (%) | 65.9 (±31.2) | 69.9 (±29.4) | 47.6 (±32.9) | < 0.001 |
ADA (IU/L) | 84.6 (±54.1) | 99.3 (±49.3) | 20.9 (±9.2) | < 0.001 |
ADA2 (% of total ADA) | 63.7 (±11.7) | 63.4 (±12.0) | 65.4 (±10.2) | 0.355 |