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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: Cigarette and IL-17A synergistically induce bronchial epithelial-mesenchymal transition via activating IL-17R/NF-κB signaling

Fig. 5

Vimentin expression in bronchial epithelial cells. When bronchial epithelial cells were stimulated with cigarette smoke extract (CSE) or/and IL-17A, Vimentin expression in cells was detected using immunofluorescence staining. Vimentin expression in CSE group was higher than that in controls, and was highest in CSE + IL-17A group. When NF-κB was inhibited, Vimentin expression was decreased in cells stimulated with CSE and CSE + IL-17A after NF-κB inhibited compared to those without inhibition. a Vimentin expression in control group without NF-κB inhibition. b Vimentin expression in CSE group without NF-κB inhibition. c Vimentin expression in IL-17A group without NF-κB inhibition. d Vimentin expression in CSE + IL-17A group without NF-κB inhibition. e Vimentin expression in control group with NF-κB inhibition. f Vimentin expression in CSE group with NF-κB inhibition. g Vimentin expression in IL-17A group with NF-κB inhibition. h Vimentin expression in CSE + IL-17A group with NF-κB inhibition. (× 400 magnification)

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