First author, year | Country | Type of study | Case (Number/aMean age/cMale) | Control (Number/ aMean age/cMale) | Case (bBMI/ dAHI means) | Control (bBMI/ dAHI means) | Method | Method features | ||
---|---|---|---|---|---|---|---|---|---|---|
S100B | NSE | S100B | NSE | |||||||
Jordan, 2002 [10] | Germany | CS | 19/50.6/100 | NA | 32.8/− | NA | – | Cobas Core NSE enzyme immunoassay (EIA) kit of Hoffmann-La Roche AG (Basel, Switzerland) | – | The detection limit of this assay was 0.02 μg/L |
Braga, 2006 [15] | Brazil | CC | 29/38/100 | 17/35/100 | 25.9/27 | 26.9/2 | Immunoluminescent assay kit (LIA-mat Sangtec 100 BYK-Sangtec, Germany) | ECLIA kit (Roche Diagnostics Corporation, USA) | Standard curve was linear up to 20 mg/L, and the coefficient variation was within 5%. | The coefficient of variation was less than 5% |
Sonka, 2007 [16] | Czech Republic | CS | 60/51.7/100 | NA | NA | NA | ECLIA kit (Roche Diagnostics Corporation, USA) | – | – | – |
da Silva, 2008 [17] | Brazil | CS | 25/39.92/40 | NA | 47.86/36 | NA | Immunoluminescent assay kit (LIA-mat Sangtec 100 BYK-Sangtec, Germany) | Elecsys-2010 (Roche Diagnostics Corporation®) | Standard curve was linear up to 20 mg/L, and the coefficient of variation was within 5%. | The coefficient of variation was less than 5% |
Ergün, 2010 [18] | Turkey | CC | 37/47/73 | 30/42/76.7 | 28.4/37 | 28.2/1 | – | Radioimmunassay | – | Nor mal range was considered as 5–14 μmol/L |
Duru, 2012 [19] | Turkey | CC | 43/47.2/58.1 | 25/43.7/68 | 29.6/37.5 | 27/37.4 | ELISA kit (Dia Metra, Italy) | – | – | – |
Oztürk, 2012 [20] | Turkey | CC | 26/56/80.7 | 28/56/71.4 | 28.8/51 | 27.7/− | ELISA kit (Bio Vendor Research and Diagnostic Products, Czech Republic) | – | Intra-assay and the inter-assay variation coefficients were 3.8 and 5.2%, respectively. Assay range was 0.05–2 μg/L | – |
Traxdorf, 2016 [21] | Germany | CC | 34/46.5/91.2 | 20/30.5/75 | 27.2/24.2 | 22.5/− | ELISA kit (Human S100B ELISA plate, Millipore, Darmstadt, Germany) | – | Cut-off limit of 0.10 μg/L (The approximate range of the system was 2.7–2000 pg/mL with a CV of 3% in intra-assay and 2–4.4% in the inter-assay analysis.) | – |
Riad, 2017 [22] | Egypt | CC | 55/44.1/56.4 | 34/45.1/50 | 35.7/12 | 30.6/2 | ELISA kit (R&D Systems, Minneapolis, Minnesota) | – | The area under the curve was 0.998 with 96.4 sensitivity and 99.7% specificity at cutoff value of 21 | – |