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Table 1 Clinical and Physiologic Characteristics in Patients with HP

From: Chronic hypersensitivity pneumonitis in the southeastern United States: an assessment of how clinicians reached the diagnosis

Characteristics

All patients (N = 261)

Demographics

 Age of diagnosis, y

57 ± 14

 Female sex

157 (60.1)

 Race

  Caucasian/White

217 (83.1)

  African American/Black

29 (11.1)

  American Indian

1 (0.3)

  Multiracial

1 (0.3)

  Other

6 (2.3)

  Not reported

7 (2.7)

 Cigarette smoking status

  Nonsmoker

142 (54.4)

  Former/Current Smoker

94 (36.0)

  Not reported

23 (8.8)

 Exposure

  Identified IA

181 (69.3)

  Unidentified IA

80 (30.7)

 Type of Exposure

  Mold

78 (43.1)

  Bird

47 (26)

  Hot tub

3 (1.7)

  Dust

14 (7.7)

  Farmer’s lung

13 (7.2)

  Occupational

10 (5.5)

  Drugs

11 (6.1)

 Positive ANA

50 (19.2)

 Pulmonary function tests, % predicted

  TLC

71 ± 21

  RV

73 ± 36

  FVC

68 ± 22

  FEV1

67 ± 22

  FEV1/FVC

78 ± 10

  DLCO

60 ± 25

 CT findings

89 (34.1)

  Mosaic attenuation

39 (14.9)

  Centrilobular nodules

16 (6.1)

  Bronchiectasis

38 (14.6)

  Fibrosis

11 (4.2)

  Nonspecific imaging

12 (4.6)

 Biopsy obtained

120 (49.4)

  VATS

92 (76.7)

  Classical TBB

13 (10.8)

  Both

15 (12.5)

  1. Values are given as the mean ± SD or No. (%). HP Hypersensitivity pneumonitis, IA Inciting antigen, TLC Total lung capacity, RV Residual volume, FVC Forced vital capacity, FEV1 Forced expiratory volume in one second, DLCO Diffusing capacity of lung for carbon monoxide, VATS Video assisted thoracoscopic surgery, TBB Trans-bronchial biopsy. Nonspecific imaging included scattered ground glass opacity (GGO), peripheral consolidation, interstitial infiltrate, transient GGO