The association of delta neutrophil index with the prognosis of acute exacerbation of chronic obstructive pulmonary disease

Table 2 Laboratory and microbiologic findings between AECOPD with and without CAP

Variables (at the time of admission)	AECOPD with CAP		P-value	AECOPD without CAP		P-value
Variables (at the time of admission)	Readmission ≤ 30 days (n = 19)	Readmission > 30 days (n = 121)	P-value	Readmission ≤ 30 days (n = 22)	Readmission > 30 days (n = 152)	P-value
Laboratory findings, mean ± SD
Oxygen saturation, %	88.3 ± 8.7	88.5 ± 10.0	0.926	86.8 ± 10.6	90.6 ± 8.9	0.153
PaO₂, mm Hg	62.6 ± 15.1	62.5 ± 15.4	0.973	61.2 ± 16.5	64.4 ± 15.0	0.104
PaCO_2, mmHg	46.9 ± 30.1	38.2 ± 12.7	0.231	43.3 ± 18.5	40.1 ± 13.4	0.438
WBC, × 10³/μL	14.7 ± 6.9	13.0 ± 5.7	0.239	11.6 ± 6.4	10.2 ± 4.5	0.205
DNI, %	9.5 ± 9.2	5.0 ± 4.6	0.049	2.9 ± 2.6	1.7 ± 2.6	0.039
Hemoglobin, g/dL	12.0 ± 1.8	13.0 ± 1.8	0.029	12.6 ± 1.5	13.1 ± 1.9	0.198
hs-CRP, mg/dL	16.4 ± 8.3	15.9 ± 9.4	0.839	2.3 ± 2.3	3.2 ± 5.8	0.472
^aProcalcitonin, mg/dL	8.1 ± 21.2	3.8 ± 7.4	0.467	1.3 ± 3.7	1.9 ± 6.1	0.753
Microbiologic findings, n (%)
Streptococcus pneumoniae	7 (36.8)	47 (38.8)	0.868	1 (4.5)	2 (1.3)	0.335
Staphylococcus aureus	3 (15.8)	16 (13.2)	0.724	2 (9.1)	18 (11.8)	1.000
Pseudomonas aeruginosa	1 (5.3)	16 (13.2)	0.468	1 (4.5)	15 (9.9)	0.697
Klebsiella pneumoniae	2 (10.5)	5 (4.1)	0.297	1 (4.5)	10 (6.6)	1.000
^bOthers	0 (0.0)	5 (4.1)	1.000	0 (0.0)	2 (1.3)	1.000

AECOPD acute exacerbations of chronic obstructive pulmonary disease, CAP community-acquired pneumonia, DNI delta neutrophil index, hs-CRP high sensitive C-reactive protein, n number, PaCO₂ arterial carbon dioxide partial pressure, PaO₂ arterial oxygen partial pressure, SD standard deviation, WBC white blood cell
^aInitial procalcitonin results were available for 81 patients in AECOPD with CAP and 94 patients in AECOPD without CAP
^bOthers were included Mycoplasma pneumoniae (2), Legionella pneumophila (1), Haemophilus influenzae (1) and Acinetobacter baumannii (1) in AECOPD with CAP, and Legionella pneumophila (1) and Haemophilus influenzae (1) in AECOPD without CAP, respectively

ISSN: 1471-2466