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Table 1 Correlation of ACT-measured improvement with improvement in other outcomes

From: Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review

Outcome

Number of studies, na

Studies reporting correlation, n (n reporting statistical significance)

Studies reporting association, n (n reporting statistical significance)

Asthma Control Questionnaire

7

68–13 (5)8–12

114 (0)

Use of rescue medication

10

215,16 (2)15,16

817–24 (4)17,18,22,23

Number of asthma exacerbations

10

226,27(2) 26,27

817,22,23,28–32 (7)22,23,28–32

Lung function

17

83,15,27,33–37 (5b)3,34–37

911,13,18,38–43 (7b)11,13,38–40,42,43

General HRQoL

7

0 (0)

749–55 (5b)49,50,52–54

Asthma-related QoL

7

528,34,44–46(5)28,34,44–46

247,48 (2)47,48

Sleep quality

6

245,56(2)45,56

556–60 (2b)58,59

Work and productivity

7

163 (1)63

649,51,53,55,64,65 (2)49,65

Healthcare resource use

17

163 (0)

1647,49,51,53–55,67–76 (8b)54,55,67,69,71,72,74,75

Healthcare costs

6

0 (0)

650,65,70,76–78 (1b)77

  1. “Correlation” denotes a direct, statistically tested relationship between ACT score and the outcome. Statistical analyses included the Pearson’s chi-square test and the Spearman correlation test. “Associations” are defined as trends between subgroups or over time, assessed by covariance tests, regression analyses, or empirical observation. ACT Asthma Control Test, HRQoL health-related quality of life, QoL quality of life
  2. aNumber of studies reporting on a particular outcome is presented per row; studies could report multiple outcomes within one topic
  3. bPublications that did not assess the significance were not taken into account for this calculation