| VM | HFNC | Difference (95% CI) | P-value** |
---|---|---|---|---|
Good responder* | 15 (75%) | 13 (65%) | Â | Â |
Primary endpoint | ||||
 Endurance time, min | 7.6 (5.0–10.1) | 6.8 (4.3–9.3) | − 0.8 (− 4.4–2.8) | 0.669 |
Secondary endpoint | ||||
 Min SpO2, % | 89.4 (85.1–93.7) | 89.7 (85.3–94.0) | 0.3 (− 5.8–6.3) | 0.934 |
 Max HR, bpm | 124.2 (115.9–132.4) | 120.8 (112.5–129.1) | −3.8 (− 11.7–4.2) | 0.345 |
 Isotime Borg scale (dyspnea) | 5.9 (4.6–7.1) | 5.9 (4.7–7.1) | 0.1 (− 1.7–1.8) | 0.955 |
 Isotime Borg scale (leg fatigue) | 5.7 (4.2–7.2) | 5.4 (3.9–6.8) | − 0.3 (− 2.4–1.8) | 0.757 |
 Final Borg scale (dyspnea) | 7.0 (5.8–8.1) | 6.6 (5.4–7.8) | − 0.4 (− 2.0–1.3) | 0.672 |
 Final Borg scale (leg fatigue) | 6.4 (4.9–7.9) | 6.3 (4.8–7.8) | − 0.1 (− 2.3–2.1) | 0.926 |
 Patient comfort of device | 7.8 (6.7–8.9) | 6.3 (5.2–7.4) | − 1.5 (− 3.1–0.1) | 0.067 |