Skip to main content

Table 2 Left ventricle standard echo and 2D speckle tracking echo measurements at rest and peak effort

From: Subclinical impairment of dynamic left ventricular systolic and diastolic function in patients with obstructive sleep apnea and preserved left ventricular ejection fraction

Variable

OSA

Controls

P-value

(n = 55)

(n = 35)

Resting measurements

 SpO2 (%)

94.7 ± 16.2

98 ± 1.6

< 0.01

 IVSd (mm)

11.4 ± 1.8

9.1 ± 2.3

<  0.01

 PWd (mm)

10.4 ± 1.6

8.7 ± 2.1

<  0.01

 LVEDD (mm)

48.3 ± 3.9

47.2 ± 4.4

NS

 LVESD (mm)

34.3 ± 3.6

32.4 ± 4.1

NS

 LV mass index (g/m2)

52.8 ± 5.3

48.1 ± 3.4

<  0.01

 Biplane LVEF (%)

56.5 ± 6.2

57.4 ± 5.5

NS

 LV GLS (%)

−13.4 ± 3.8

−18.4 ± 3.3

< 0.001

 Mitral E velocity (cm/s)

0.9 ± 0.3

0.8 ± 0.4

NS

 Mitral A velocity (cm/s)

0.7 ± 0.4

0.9 ± 0.3

NS

 E/A ratio

1.2 ± 0.4

0.9 ± 0.4

<  0.01

 Mitral septal e’ velocity (cm/s)

0.13 ± 0.02

0.16 ± 0.05

<  0.01

 Mitrallateral e’ velocity (cm/s)

0.14 ± 0.03

0.17 ± 0.03

<  0.01

 E/e’ ratio

8.2 ± 3.1

5.9 ± 2.8

<  0.01

 LAVI (ml/m2)

32.4 ± 4.4

28.3 ± 5.1

<  0.01

 sPAP (mmHg)

31.5 ± 7.8

21.3 ± 2.9

<  0.01

 TAPSE (mm)

22.5 ± 3.3

24.5 ± 3.8

NS

 Tricuspid S′ velocity (cm/s)

13.3 ± 2.2

14.4 ± 3.1

NS

Peak effort measurements

 SpO2 (%)

92.3 ± 3.2

97.2 ± 2.6

< 0.01

 Exercise capacity (Watt)

115.3 ± 25

150.4 ± 35

<  0.001

 Biplane LVEF (%)

62.3 ± 5.8

65.7 ± 6.8

NS

 LV GLS (%)

−15.8 ± 2.6

−23.4 ± 4.3

< 0.001

 Mitral E velocity (cm/s)

1.1 ± 0.5

1.2 ± 0.6

NS

 Mitral A velocity (cm/s)

0.9 ± 0.4

0.9 ± 0.3

NS

 E/A ratio

1.2 ± 0.4

1.3 ± 0.5

<  0.01

 Mitral septal e’ velocity (cm/s)

0.08 ± 0.02

0.18 ± 0.05

< 0.0001

 Mitral lateral e’ velocity (cm/s)

0.07 ± 0.03

0.19 ± 0.03

< 0.0001

 E/e’ ratio

15.4 ± 4.1

7.4 ± 2.8

< 0.0001

 sPAP (mmHg)

45.5 ± 5.8

28.4 ± 4.2

< 0.001

 TAPSE (mm)

26.4 ± 2.3

27.5 ± 5.8

NS

 Tricuspid s’ velocity (cm/s)

16.4 ± 3.1

17.7 ± 4.1

NS

  1. Data are expressed as mean ± SD. Statistically significant results (p < 0.05) are reported in bold
  2. Abbreviations: SpO2 Arterial oxygen saturation, IVSd Inter-ventricular septum thickness at end diastole, PWd Posterior wall thickness at end diastole, LVEDD Left ventricular end diastolic diameter, LVESD Left ventricular end systolic diameter, LV Left ventricle, LVEF Left ventricular ejection fraction, LV GLS Left ventricular global longitudinal strain, LAVI Left atrial volume index, sPAP Systolic pulmonary artery pressure, TAPSE Tricuspid annular plane systolic excursion