Table 2 Disease burden and results of investigations in Severe Asthma Clinic patients

Hospital Admissions in the previous year

10 (43)^c

Number of Hospital admissions in the previous year

3/3(0.9/1–4)^d

Number of children with Positive Skin Prick Test

19 (83)^c

Number of children with serum Specific IgE positive

18 (78)^c

 ● Aspergillus

4 (22) ^c

 ● D pteronys

15 (65) ^c

 ● Australia treemix

4 (22) ^c

 ● Cat epithelia

7 (30) ^c

 ● Dog dander

9 (50) ^c

 ● Weed mix

4 (22) ^c

 ● Grass mix

7 (30) ^c

 ● Mould mix

4 (22) ^c

Blood eosinophils levels^a

909/800 (66/0–2900) ^d

Serum Immunoglobulin E (IU/mL) ^a

1257/1210 (1125/165–4565)^d

Age at symptoms onset in years^a

3.7/1.5 (3.9/0.5–12) ^d

Age at visit date in years

11.4/12 (2.7/4–16) ^d

ICS^b (mcg/day)

1851/2000 (642/640–4000) ^d

Number of children with ACT score ≤ 19

17 (74) ^c

ACT score

14.2/12 (5.4/8–25) ^d

Quality of Life Questionnaire score ^a

5.2/5.3 (1.1/3.1–7) ^d

ACQ-5^a

1.8/1.8 (1/0–3.8)^d

PI-ED

9(38)^c

 ● Anxiety

 ● Depression

5/3 (6.6/0–20)

0.6/0 (1.3/0–3)

Number of children under treatment with Azithromycin

7 (30) ^c

Nasal steroids

16 (70)^c

Bronchoscopy

9 (39^c)

Bronchoalveolar Lavage Fluid (BALF)^a

7 (30) ^c

 ● % Macrophage

86.4/88 (12.6/68–99.5) ^d

 ● % Eosinophil

2.8/1.3 (7.5/0.5–21) ^d

 ● % Lymphocyte

7.9/7.5 (8.8/0.5–26) ^d

 ● % Neutrophil

4.7/1 (8.0/0.5–19) ^d