Table 4 Pulmonary function test at first visit and follow-up of SAC children who attended both visits

n = 16

Mean/median (SD/min-max)

n = 16

Mean/median (SD/min-max)

p value

FVC litres pre BD

2.5/2.6 (0.6/1.6–3.7)

3.7/3.4 (1.3/1.4–6.7)

0.0002

FVC % pre BD

92.2/95.5 (13.1/64–109)

100.6/101 (10.2/81/114)

0.053

FEV1 litres pre BD

1.7/1.7 (0.4/1.1–2.5)

2.7/2.1 (0.9/1.2–4.9)

< 0.0001

FEV1% pre BD

69.8/71.5 (14.4/40–91)

84.1/85 (10.9/59–107)

0.0009

Abnormal FEV1% pre BD

10(63)

5(31)

0.077

FEV1/FVC litres pre BD

66.9/67.3 (8.7/47.7–88.4)

75.3/74.0 (8.4/64.7–95.3)

0.002

FVC litres post BD

2.6/2.7 (0.6/1.6–3.9)

3.8/3.5 (1.3/1.5–6.8)

0.0002

FVC % post BD

97.7/102 (12.1/75–117)

103.5/105 (9.6/84–116)

0.136

FEV1 litres post BD

1.8/1.8 (0.4/1.2–2.7)

2.9/2.9 (1.0/1.3–5.6)

0.0003

FEV1% post BD

78.5/71.2 (13.7/47–98)

89.9/92 (13.2/66–118)

0.006

FEV1/FVC litres post BD

71.2/72.3 (9.3/55.7–92.9)

76.5/76.2 (10.6/54–98.3)

0.073

BDR %

13/8 (13/3–45)

8/6 [7.7/(−4)-23]

0.224

BDR ≥ 12%^a

5(31)

6(38)

0.710

ACT score^b

14/12 (5/8–25)

18/18 (5/12–25)

0.009

Percentage of ACT score ≤ 19^a

12(75)

9(56)

0.264

TLC%

117/113 (24/88–184)

105/104 (13/86–140)

0.094

TLC litres

4/4 (1/3–6)

11/5 (24/2–101)

0.262

RV/TLC %

171/181 (40/112–254)

131/130 (32/77–199)

< 0.0001

Abnormal RV/TLC%

12(75)

5(31)

0.013

n = 6

Mean/median (SD/min-max)

n = 6

Mean/median (SD/min-max)

LCI

11.0/10.7 (1.7/8.6–13.6)

9.5/8.5 (2/7.2–12.8)

0.237

Abnormal LCI (%)^a

6(100)

5(83)

0.297

FRC/body weight (mL/kg)

51.9/52.9 (10.5/38–62.3)

58.4/59.5 (17.9/34–79.9)

0.104

FeNO (ppb)^b

30/19 (26/6–87)

36/31 (33/4–100)

0.390

Abnormal FeNO^a

5(42)^b

6(50)^b

0.682