Skip to main content

Table 2 Specific diagnoses prompting hospital admissions, outpatient clinic visits or emergency department visits

From: Increased respiratory morbidity in individuals with interstitial lung abnormalities

Diagnosis

ILA (%)

No ILA (%)

HR

95% CI

Adjusted p-value

Respiratory

116 (34.9)

361 (21.8)

1.6

1.3–2.0

<  0.001

 COPD

55 (16.6)

159 (9.6)

1.7

1.2–2.3

0.01

 Pneumonia

56 (16.9)

126 (7.6)

2.0

1.4–2.7

<  0.001

 Asthma

4 (1.2)

47 (2.8)

0.4

0.2–1.2

0.15

 Pleural empyema or lung abscess

5 (1.5)

3 (0.2)

6.6

1.5–28.8

0.03

 Interstitial lung disease

8 (2.4)

8 (0.5)

4.9

1.8–13.3

0.008

 Respiratory failure

25 (7.5)

61 (3.7)

1.8

1.1–3.0

0.03

Malignant neoplasm

93 (28.0)

317 (19.1)

1.4

1.1–1.8

0.02

 Lung cancer

39 (11.7)

71 (4.3)

2.7

1.8–4.0

<  0.001

 Non-pulmonary cancer

67 (20.2)

266 (16.0)

1.2

0.9–1.6

0.30

Cardiovascular

157 (47.3)

652 (39.3)

1.2

1.0–1.5

0.09

 Heart failure

19 (5.7)

47 (2.8)

1.7

1.0–3.0

0.19

 Pulmonary embolism

8 (2.4)

22 (1.3)

1.9

0.8–4.3

0.17

 Atrial fibrillation/atrial flutter

27 (8.1)

95 (5.7)

1.3

0.8–2.0

0.34

 Ischemic heart disease

50 (15.1)

174 (10.5)

1.4

1.0–2.0

0.07

 Cerebral infarction

18 (5.4)

59 (3.6)

1.4

0.8–2.3

0.34

 Peripheral vascular disease

21 (6.3)

50 (3.0)

2.0

1.2–3.4

0.04

Gastrointestinal

125 (37.7)

489 (29.5)

1.3

1.1–1.6

0.02

 GORD, gastritis or ulcer disease

25 (7.5)

95 (5.7)

1.3

0.8–2.1

0.30

 Functional intestinal disorders

28(8.4)

66(4.0)

2.2

1.4–3.4

0.006

Musculoskeletal system and connective tissue

140 (42.2)

739 (44.6)

1.0

0.8–1.2

0.89

 Inflammatory polyarthropathies

8 (2.4)

57 (3.4)

0.7

0.3–1.5

0.40

  1. ILA interstitial lung abnormalities, HR hazard ratio, COPD chronic obstructive pulmonary disease, GORD gastro-oesophageal reflux disease
  2. Number of participants with ILA compared with participants without ILA for receiving one of several specific diagnoses of interest at a hospital admission, outpatient clinic visits or emergency department visit. Cox regression analysis is adjusted for age, sex, BMI and pack-years. P-values are adjusted for multiple comparisons by the Benjamini-Hochberg method