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Table 6 Association of P. jirovecii colonization with laboratory findings of the patients

From: Pneumocystis jirovecii colonization and its association with pulmonary diseases: a multicenter study based on a modified loop-mediated isothermal amplification assay

 

Positive

Negative

Total

Positive rate (%)

Serum BDG levels

 Positive (> 10 pg/ml)

34

5

39

81.18a

 Negative (< 10 pg/ml)

128

50

178

71.91

Serum PCT levels

 Positive (> 0.5 ng/mL)

59

22

81

72.84b

 Negative (< 0.5 ng/mL)

103

33

136

75.74

Serum LDH levels

 Positive (> 225 U/L)

84

33

117

71.79c

 Negative (< 225 U/L)

197

89

286

68.88

Serum CRP levels

 Positive (> 5 mg/L)

171

59

230

74.35d

 Negative (< 5 mg/L)

110

63

173

63.58

ESR test

 Abnormal

78

33

111

70.27e

 Normal

109

51

160

68.13

Thoracic HRCT findings

 GGO positive

67

14

81

82.72f

 GGO negative

95

41

136

69.85

Pulmonary function

 FEV1/FVC positive (<  70%)

25

6

31

80.65g

 FEV1/FVC negative (>  70%)

14

11

25

56.00

CD4+ T-cell count

 <  410/mm3

23

2

25

92.00h

 >  410/mm3

53

24

77

68.83

  1. Abbreviations: BDG 1,3-β-D-glucan, PCT pro-calcitonin, LDH lactate dehydrogenase, CRP C-reactive protein, ESR erythrocyte sedimentation rate, GGO ground-glass opacity, HRCT high-resolution computed tomography, FEV1 forced expiratory volume in one second, FVC forced vital capacity
  2. aP < 0.05, > 0.01, Compared with serum BDG < 10 pg/mL
  3. bP > 0.05 Compared with serum PCT < 0.5 ng/mL
  4. cP > 0.05 compared with LDH levels < 225 U/L
  5. dP < 0.05, > 0.01, compared with CRP negative (< 5 mg/L)
  6. eP > 0.05 compared with ESR normal. ESR abnormal (> 15 mm/h for men and > 20 mm/h for women). ESR normal (≤ 15 mm/h for men and ≤ 20 mm/h for women)
  7. fP < 0.05, > 0.01, compared with GGO negative
  8. gP < 0.05, > 0.01, compared with FEV1/FVC negative (> 70%)
  9. hP < 0.05, > 0.01, compared with CD4+ T-cell count > 410/mm3