| Neuromuscular disease/ Kyphoscoliosis N = 20a | Bronchiectasis N = 24a | COPD N = 24a |
---|---|---|---|
N (%) | |||
Diagnosis | Neuromuscular disease: 18 Kyphoscoliosis: 2b | Bronchiectasis: 24 Cystic Fibrosis: 0 | COPD: 24 |
Male | 8 (40%) | 7 (29%) | 12 (50%) |
Home NIV | 4 (20%) | 2 (8%) | 1 (4%) |
Home oxygen | 1 (5%) | 0 (0%) | 0 (0%) |
Smoking status | Total N = 18c | Total N = 23c | Total N = 18c |
- Current | 1 (6%) | 0 (0%) | 3 (17%) |
- Ex | 7 (39%) | 3 (13%) | 15 (83%) |
- Never | 10 (56%) | 20 (87%) | 0 (0%) |
Mean (SD) | |||
Age (years) | 52.2 (14.9) | 63.0 (12.0) | 69.4 (7.3) |
BMI (kg/m2) | 25.3 (7.2) | 27.1 (4.7) | 27.9 (4.8) |
Smoking pack years | 4.2 (9.1) | 0.6 (2.2) | 35.5 (22.9) |
FEV1 percentage predicted (%) | 57.6 (20.5) | 69.9 (22.4) | 65.7 (17.3) |
FVC percentage predicted (%) | 57.7 (20.5) | 87.4 (21.5) | 97.5 (17.9) |
FEV1/FVC ratio (%) | 83.0 (7.3) | 64.6 (12.2) | 53.5 (11.1) |
PtCO2 (mmHg) | 38.7 (4.8) | 36.6 (3.4) | 35.7 (3.5)d |
- Min to max | 27.8 to 48.6 | 29.3 to 42.8 | 29.8 to 42.1 |
Oxygen saturation (%) | 95.7 (2.4) | 96.3 (1.3) | 95.4 (2.5)d |
- Min to max | 91 to 100 | 93 to 99 | 87 to 99 |
Respiratory rate (breaths/minute) | 18.8 (4.5) | 16.8 (3.2) | 17.0 (3.9) |
Neuromuscular disease/kyphoscoliosis study entry criteria and diagnoses, N | |||
Participants with SNIP < 95% rangee | 12 | NA | NA |
Participants with VC drop ≥10% sitting to lyingf | 13 | NA | NA |
Neuromuscular Diagnosis | Â | NA | NA |
- Charcot Marie Tooth | 3 | Â | Â |
- Facioscapulohumeral muscular dystrophy | 2 | Â | Â |
- Limb girdle muscular dystrophy | 1 | Â | Â |
- Motor neurone disease | 5 | Â | Â |
- Multiple sclerosis | 1 | Â | Â |
- Myotonic dystrophy | 4 | Â | Â |
- Phrenic nerve palsy | 1 | Â | Â |
- Tetraplegia | 1 | Â | Â |