| Neuromuscular disease/ Kyphoscoliosis | Bronchiectasis | COPD | ||||||
---|---|---|---|---|---|---|---|---|---|
Oxy T = 0 Mean (SD) N = 18 | Air T = 0 Mean (SD) N = 20 | Estimate (95% CI) P valuea | Oxy T = 0 Mean (SD) N = 24 | Air T = 0 Mean (SD) N = 23 | Estimate (95% CI) P valuea | Oxy T = 0 Mean (SD) N = 24b | Air T = 0 Mean (SD) N = 24b | Estimate (95% CI) P valuea | |
Minute ventilation (L/min) | 6.8 (2.0) | 6.3 (2.0) | 0.17 (−0.26 to 0.59) P = 0.44 | 7.56 (2.49) | 7.13 (1.88) | 0.41 (−0.1 to 0.89) P = 0.09 | 8.08 (2.72) | 8.03 (2.48) | −0.13 (− 0.55 to 0.29) P = 0.55 |
Respiratory rate (breaths/minute) | 15.7 (5.1) | 15.9 (5.6) | −0.01 (− 0.73 to 0.71) P = 0.98 | 15.5 (2.9) | 14.7 (3.1) | 0.4 (−0.4 to 1.2) P = 0.34 | 15.4 (5.0) | 14.5 (4.4) | −0.3 (−1.0 to 0.3) P = 0.31 |
Tidal volume (L) | 0.48 (0.21) | 0.44 (0.2) | 0.004 (−0.024 to 0.033) P = 0.77 | 0.50 (0.2) | 0.50 (0.15) | 0.01 (−0.03 to 0.05) P = 0.65 | 0.56 (0.18) c | 0.58 (0.17) c | −0.003 (− 0.03 to 0.03) P = 0.82 |
Alveolar minute ventilation (L/min) | 3.18 (1.28) | 2.88 (1.33) | −0.03 (− 0.24 to 0.18) P = 0.78 | 3.26 (1.23) | 3.10 (1.05) | −0.06 (− 0.26 to − 0.15) P = 0.58 | 3.16 (0.94) c | 3.15 (0.76) c | −0.21 (− 0.38 to − 0.04) P = 0.014 |
Alveolar volume (L) | 0.24 (0.15) | 0.21 (0.13) | − 0.01 (− 0.023 to 0.01) P = 0.44 | 0.22 (0.10) | 0.22 (0.09) | −0.02 (− 0.04 to 0.01) P = 0.14 | 0.23 (0.10) c | 0.24 (0.11) c | − 0.01 (− 0.03 to 0.001) P = 0.065 |
ETCO2 (mmHg) | 34.1 (2.9) | 33.7 (3.4) | −0.20 (−1.0 to 0.60) P = 0.62 | 31.8 (3.6) | 31.2 (4.4) | −1.0 (− 1.7 to − 0.3) P = 0.004 | 29.0 (3.9) | 29.2 (4.0) | −1.1 (− 1.7 to − 0.5) P < 0.001 |
Volume of dead space (L) | 0.24 (0.09) | 0.23 (0.08) | 0.012 (− 0.004 to 0.027) P = 0.13 | 0.28 (0.10) | 0.28 (0.07) | 0.01 (0.006 to 0.05) P = 0.011 | 0.33 (0.09) c | 0.33 (0.09) c | 0.009 (−0.007 to 0.03) P = 0.27 |
VD/VT | 0.54 (0.11) | 0.56 (0.09) | 0.009 (−0.004 to 0.023) P = 0.17 | 0.57 (0.06) | 0.57 (0.07) | 0.03 (0.02 to 0.04) P < 0.001 | 0.60 (0.07) c | 0.59 (0.09) c | 0.023 (0.01 to 0.037) P < 0.001 |
Heart rate (beats per minute) | 69.7 (13.8) | 68.7 (13.3) | 0.42 (−1.0 to 1.9) P = 0.56 | 73.7 (10.0) | 74.9 (11.7) | −1.5 (−2.8 to −0.1) P = 0.036 | 71.9 (11.7) c | 69.9 (11.8)c | −3.3 (− 4.6 to − 2.1) P < 0.001 |