People–centred care versus clinic–based DOT for continuation phase TB treatment in Armenia: a cluster randomized trial

Table 5 Regression analysis of TB patients’ and their family members’ non–clinical outcomes by intervention

Random intercept model^a	TB patients				Family members
Random intercept model^a	Beta estimate	95% confidence limits		P–value	Beta estimate	95% confidence limits		P–value
Knowledge score change^b
Intervention	1.05	0.49	1.60		2.02	1.30	2.75
Control	1.09	0.56	1.64		1.43	0.60	2.27
Difference (Intervention – Control)	−0.05	−0.82	0.73	0.73	0.59	−0.52	1.70	0.29
Depression score change^b
Intervention	−3.56	−4.99	−2.13		− 3.44	−4.96	−1.92
Control	−1.88	−3.26	−0.49		− 1.78	−3.53	−0.02
Difference (Intervention – Control)	−1.68	−3.67	0.30	0.10	− 1.66	−3.98	0.66	0.16
Stigma score change^b
Intervention	0.23	−0.33	0.80		− 0.73	−1.25	−0.22
Control	−0.28	−0.84	0.27		− 0.99	−1.59	−0.39
Difference (Intervention – Control)	0.52	−0.27	1.31	0.20	0.26	− 0.53	1.05	0.52
Support score change^b
Intervention	1.02	−0.25	2.28		−0.04	−0.97	0.90
Control	0.06	−1.15	1.27		− 0.43	−1.50	0.64
Difference (Intervention – Control)	0.95	−0.80	2.70	0.28	0.40	−1.03	1.82	0.58
Quality of life score change^b
Intervention	5.01	−0.64	10.66
Control	7.29	1.77	12.81
Difference (Intervention – Control)	−2.28	10.18	5.61	0.57

^aMixed effect models including random effect for TB clinics and subjects (random intercepts)
^bChange is the difference in the outcome measure at the follow-up and baseline

ISSN: 1471-2466