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Table 2 Comparison of the symptoms and laboratory data in patients with pulmonary cryptococcosis, according to eGFR

From: Clinical impact of advanced chronic kidney disease in patients with non-HIV pulmonary cryptococcosis

 

eGFR > 45

eGFR ≤45

p value

n

42

14

 

Asymptomatic

15 (35.7%)

2 (14.3%)

0.11

Cough

12 (28.6%)

6 (42.9%)

0.32

Sputum

6 (14.3%)

4 (28.6%)

0.24

Chest pain

4 (9.5%)

1 (7.1%)

0.78

Fever (>  37.5 °C)

8 (19.0%)

8 (57.1%)

< 0.01

Dyspnea

2 (4.8%)

1 (7.1%)

0.74

Laboratory data

 WBC (/mL)a

6150 ± 5100

8550 ± 7575

0.01

 Lymphocyte cell (/mL)a

1151.6 ± 740.4

1326.9 ± 518.0

0.87

 Serum albumin (g/dL)a

3.8 ± 3.4

3.0 ± 2.6

< 0.01

 Serum calciuma b

9.6 ± 9.0

9.3 ± 9.1

0.88

 Immunoglobulin G (mg/dL)a

903.5 ± 745.3

1233.5 ± 621.5

0.48

 CRP (mg/dL)a

0.2 ± 0.1

2.1 ± 0.2

0.02

 Anti-cryptococcus antigena

16 ± 1

8 ± 5

0.48

  1. WBC White blood cell, CRP C reactive protein, eGFR estimated glomerular filtration rate
  2. a Data are presented as median ± interquartile range
  3. b corrected by serum albumin