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Table 1 Comparison of baseline characteristics of lung cancer patients with or without pneumonia

From: Smoking is associated with pneumonia development in lung cancer patients

CharacteristicPneumonia (n = 118)Non-pneumonia (n = 295)p-value
Age, year69.79 ± 8.3566.37 ± 10.600.002
Sex, male98 (83.1)205 (69.5)0.005
BMI, kg/m222.80 ± 2.94323.52 ± 3.1210.887
Smoking history  0.002
 Never17 (14.4)91 (30.8)0.001
 Former53 (44.9)113 (38.3)0.216
 Current48 (40.7)91 (30.8)0.056
 Pack-years39.85 ± 23.8339.89 ± 25.500.992
 Underlying disease97 (82.2)235 (78.9)0.444
 Accompanied cancer15 (12.7)47 (75.8)0.430
Pathology  0.004
 Adenocarcinoma53 (44.9)183 (62.0)0.002
 SqCC32 (27.1)64 (21.7)0.238
 SCLC29 (24.6)29 (9.8)< 0.001
 Adenosquamous1 (0.8)5 (1.7)0.516
 Large cell1 (0.8)2 (0.7)0.885
 NOS0 (0)1 (0.3)0.527
 Mesothelioma0 (0)0 (0) 
 Others2 (1.7)8 (2.7)0.354
Line of therapy  0.067
 07 (5.9)24 (8.2) 
 157 (48.3)139 (47.3) 
 225 (21.2)87 (29.6) 
  ≥ 329 (24.6)44 (15.0) 
Neutropenia51 (43.2)56 (18.9)< 0.001
PFT
 FVC, % pred82.25 ± 16.81087.77 ± 19.3490.218
 FEV1, % pred78.39 ± 19.21983.93 ± 22.8780.083
 FEV1/FVC < 70%47 (49.5)93 (40.8)0.151
 FEV1/FVC0.90 ± 0.2970.93 ± 0.2590.103
Clinical stage  < 0.001
 I15 (12.7)100 (33.9)< 0.001
 II10 (8.5)19 (4.6)0.476
 III47 (39.8)50 (16.9)< 0.001
 IV46 (39.0)124 (42.0)0.534
Treatment modality  < 0.001
 No therapy7 (5.9)22 (7.5)0.567
 Surgery26 (22.0)107 (36.6)0.004
 Chemotherapy47 (39.8)75 (25.7)0.005
 TKI7 (5.9)47 (16.1)0.006
 CCRT17 (14.4)18 (6.2)0.007
 SBRT0 (0)2 (0.7)0.367
 RT11 (9.3)14 (4.8)0.083
 Neo-adjuvant CCRT0 (0)3 (1.0)0.247
  1. Data are expressed as mean ± standard deviation or number (%) except where otherwise indicated
  2. Abbreviations: BMI, body mass index; SqCC, squamous cell carcinoma; SCLC, small cell lung cancer; NOS, not otherwise specified; PFT, pulmonary function test; FVC, forced vital capacity; pred, predictive value; FEV1, forced expiratory volume in 1 s; TKI, tyrosine kinase inhibitor; CCRT, concurrent chemoradiation therapy; SBRT, stereotactic body radiation therapy; RT, radiation therapy
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