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Table 1 Baseline characteristics of TB cohort participants, included in final analysis

From: Development of chronic lung impairment in Mozambican TB patients and associated risks

Characteristic

TB patients in final analysis

(N = 62)

Sex

 Male, % (n/N)

67.74 (42/62)

Age

 Median (IQR)

29.5 (25, 40)

  < 40 years old, % (n/N)

74.19 (46/62)

HIV-status

 Positive, % (n/N)

62.90 (39/62)

 CD4- cells < 200/μl, % (n/N)

46.15 (18/39)

 CD4- cells < 300–499/μl, % (n/N)

38.46 (15/39)

 CD4- cells ≥500/μl, % (n/N)

15.38 (6/39)

History of TB

 Yes, % (n/N)

6.45 (4/62)

RIF resistance

 Present, % (n/N)

6.45 (4/62)

Chronic respiratory diseasesa

 Present, % (n/N)

4.84 (3/62)

Haemoglobin

 Median male, g/dl (IQR)

11.70 (10.2, 12.6)

 Median female, g/dl (IQR)

9.90 (9.45, 11.00)

Anaemiab

 No, % (n/N)

16.13 (10/62)

 Mild, % (n/N)

37.10 (23/62)

 Moderate, % (n/N)

41.94 (26/62)

 Severe, % (n/N)

4.84 (3/62)

C-reactive protein (CRP)b,c

 Median, mg/dl (IQR)

76.78 (44.0, 106.95)

  < 50 mg/dl, % (n/N)

31.03 (18/58)

 51–100 mg/dl, % (n/N)

39.66 (23/58)

  > 100 mg/dl, % (n/N)

29.31 (17/58)

BMIb

 Median (IQR)

19.23 (17.51, 20.50)

  < 18.5, % (n/N)

41.94 (26/62)

Culture conversion

 until week 8

56.45 (35/62)

 until week 26

93.55 (58/62)

Overall affected lungc

 %, median (IQR)

15 (15, 20)

Smoking

 Ever smoked, % (n/N)

35.48 (22/62)

Pack Yearsb, c

  < 10

59.09 (13/22)

  ≥ 10

31.82 (7/22)

Alcohol consumptionb

 Ever alcohol, % (n/N)

77.42 (48/62)

 Amount of alcohol, median, g/week (IQR)

80.0 (40, 240)

 Critical alcohol consumptionc, % (n/N)

53.33 (32/60)

  1. aChronic respiratory diseases (asthma or COPD),
  2. bmissing observations: CRP for 4 participants, Pack Years (PY) for 2 participants, amount of alcohol consumption for 2 participants
  3. cdefinitions:
  4. - Anaemia, definition according to WHO, non-anaemia: 12 mg/dl or higher (women) or 13 mg/dl or higher (men), mild: 11.0–11.9 g/dl (women) and 11.0–12.9 g/dl (men), moderate: 8.0 g/dl-10.9 g/dl (both sexes), severe: < 8.0 g/dl (both sexes) [30]
  5. - CRP: normal range: 0.0 md/dl − 10 mg/dl, only one participant had a CRP value below 10 mg/dl at baseline
  6. - X-ray scoring system for reporting overall affected lung, according to Ralph et al. [21]
  7. - Pack Years (PY): lifetime exposure to cigarette smoking, e.g. ≥10PY means that the respective study participant smoked an equivalent of one pack of cigarettes every day for at least 10 years (e.g. 1 pack of cigarettes on every day for 10 years, or 2 packs of cigarettes on every day for 5 years, or ½ packs of cigarettes on every day for 20 years) at baseline study visit. PY were only calculated for those 20 male study participants who reported to have “ever smoked” during their lifetime and provided information on PY
  8. - Critical alcohol consumption: in men (women) more than 60 g (30 g) alcohol per occasion of alcohol drinking and/or more than 150 g (80 g) alcohol per week, according to the International Alliance for Responsible Drinking for general population [31]
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