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Table 2 Patients’ characteristics according to survival – univariate analysis

From: Baseline low ALT activity is associated with increased long-term mortality after COPD exacerbations

Patients’ characteristicsAliveDeadHazard ratio (95% CI)P Value
Age (years ± SD)72.89 ± 10.879.96 ± 9.21.06 (1.04–1.08)<  0.001
Norton score (number, (IQR))16.84 (15–19)14.33 (11.25–17)0.88 (0.84–0.92)<  0.001
Albumin (mg/dL ± SD)3.69 ± 0.473.48 ± 0.450.48 (0.34–0.7)<  0.001
Creatinine (mg/dL, (IQR))1.03 (0.69–1.21)1.29 (0.84–1.62)1.57 (1.23–2)<  0.001
ALT (IU/L, IQR)18.71 (13–23.75)13.77 (9–17)0.93 (0.9–0.96)<  0.001
ALT < 11 IU/L (n (%))22 (17.2%)49 (47.1%)2.48 (1.67–3.66)<  0.001
Cardiovascular disease (n (%))89 (69.5)84 (80.8)1.8 (1.1–2.93)0.019
Cardiovascular medications (n (%))101 (78.9)94 (90.4)2.09 (1.09–4.0)0.027
Neurologic medications (n (%))41 (32.0)54 (51.9)1.94 (1.31–2.86)0.001
Anticoagulation medications (n (%))29 (18.8)37 (35.6)1.73 (1.15–2.57)0.008