Table 2 Patients’ characteristics according to survival – univariate analysis
From: Baseline low ALT activity is associated with increased long-term mortality after COPD exacerbations
Patients’ characteristics | Alive | Dead | Hazard ratio (95% CI) | P Value |
|---|---|---|---|---|
Age (years ± SD) | 72.89 ± 10.8 | 79.96 ± 9.2 | 1.06 (1.04–1.08) | < 0.001 |
Norton score (number, (IQR)) | 16.84 (15–19) | 14.33 (11.25–17) | 0.88 (0.84–0.92) | < 0.001 |
Albumin (mg/dL ± SD) | 3.69 ± 0.47 | 3.48 ± 0.45 | 0.48 (0.34–0.7) | < 0.001 |
Creatinine (mg/dL, (IQR)) | 1.03 (0.69–1.21) | 1.29 (0.84–1.62) | 1.57 (1.23–2) | < 0.001 |
ALT (IU/L, IQR) | 18.71 (13–23.75) | 13.77 (9–17) | 0.93 (0.9–0.96) | < 0.001 |
ALT < 11 IU/L (n (%)) | 22 (17.2%) | 49 (47.1%) | 2.48 (1.67–3.66) | < 0.001 |
Cardiovascular disease (n (%)) | 89 (69.5) | 84 (80.8) | 1.8 (1.1–2.93) | 0.019 |
Cardiovascular medications (n (%)) | 101 (78.9) | 94 (90.4) | 2.09 (1.09–4.0) | 0.027 |
Neurologic medications (n (%)) | 41 (32.0) | 54 (51.9) | 1.94 (1.31–2.86) | 0.001 |
Anticoagulation medications (n (%)) | 29 (18.8) | 37 (35.6) | 1.73 (1.15–2.57) | 0.008 |