Fig. 4From: Multivariate joint modeling to identify markers of growth and lung function decline that predict cystic fibrosis pulmonary exacerbation onsetObserved and predicted evolution of markers of lung function and growth. Lung function (FEV1% predicted, upper left y-axis) and growth (BMIp, lower left y-axis) and probability of not having a pulmonary exacerbation (PE-free probability, upper/lower right y-axis) in a female CF F508del homozygous patient over a series of four clinical encounters (observations are black dots; mean response is black curve). Arrows illustrate how her probability of remaining PE-free is dynamically updated with each clinical encounterBack to article page