Fig. 2
Images of the lesion. a Papules localized to the right anterior and lateral chest wall. b FDG-positron emission tomography/computed tomography findings at the level of the axilla (b-i) and the nipple (b-ii). Mild uptake of 18F- fluorodeoxyglucose is observed in the subcutaneous tissue (arrows). c Schema with histological findings. i, ii: A squamous cell carcinoma showing marked lymph vessel permeation (i: hematoxylin and eosin; ii: p40 immunostaining, original magnification × 200); iii: A metastatic squamous cell carcinoma with degeneration in the right pulmonary hilar lymph node (hematoxylin and eosin stain, original magnification × 200); iv, v: Remarkable lymphatic vessel invasion in the subclavian lesion (iv: hematoxylin and eosin; v: D2-40 immunostaining, original magnification × 200); vi: The metastatic skin nodule (arrowheads) with lymph vessel permeation (arrows) (hematoxylin and eosin stain, original magnification × 100)