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Table 3 Prediction of eosinophilic exacerbation by eosinophil levels stratified in stable COPD

From: The association between eosinophilic exacerbation and eosinophilic levels in stable COPD

Cut off

AUC

P value

Sensitivity

Specificity

PPV

NPV

Eosinophilic exacerbation (cut off eosinophil 2%)

 100

0.579

0.021

81

34.8

33.5

81.9

 150

0.585

0.013

68

49.0

35.1

79.1

 300

0.614

0.001

39

83.8

49.4

77.2

 400

0.576

0.027

22

93.1

56.4

74.7

 2%

0.587

0.011

72

45.3

34.8

80

 3%

0.600

0.004

56

64

38.6

78.2

 4%

0.599

0.004

42

77.7

43.3

76.8

Eosinophilic exacerbation (cut off eosinophil 300 cells/uL)

 100

0.567

0.042

81.3

32.1

16.1

91.4

 150

0.562

0.044

66.7

45.8

16.5

89.5

 300

0.634

0.046

45.8

80.9

27.8

90.3

 400

0.616

0.048

31.3

92.0

38.5

89.3

 2%

0.577

0.043

72.9

42.5

16.9

90.7

 3%

0.608

0.044

60.4

61.2

20.0

90.6

 4%

0.616

0.046

47.9

75.3

23.7

90

  1. COPD, chronic obstructive pulmonary disease, AUC, area under the ROC curve, PPV, positive predictive value, NPV, negative predictive value