The association between eosinophilic exacerbation and eosinophilic levels in stable COPD

BMC Pulmonary Medicine

Table 4 Association between eosinophilia at the stable state and eosinophilic exacerbations

Variables	OR	95% CI	P value
Eosinophilic exacerbations (cut off eosinophil 2%)
Age	0.975	0.949–1.002	0.074
Male	2.542	1.347–4.799	0.004
Post BD FEV₁ (%)	1.008	0.994–1.021	0.252
ICS containing inhaler	2.421	1.446–4.054	0.001
Eosinophilia at stable state (cut off eosihophil 300 cells/uL)	2.962	1.704–5.150	< 0.001
Eosinophilic exacerbations (cut off eosinophil count 300 cells/uL)
Age	0.951	0.920–0.984	0.003
Male	1.113	0.524–2.366	1.113
Post BD FEV₁ (%)	1.011	0.995–1.028	1.011
ICS containing inhaler	1.921	0.977–3.777	0.059
Eosinophilia at stable state (cut off eosihophil 300 cells/uL)	3.129	1.608–6.089	0.001

OR, odds ratio, CI, confidence interval, BD, bronchodilator, FEV_1, forced expiratory volume in 1 s, ICS, inhaled corticosteroid

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