Table 1 Flow of diagnosis and treatments
From: Crazy‐paving patterns as rare radiological manifestations of pulmonary cryptococcosis: a case report
Indexes | Normal range | Hospitalization | Discharged from hospital | |||||
|---|---|---|---|---|---|---|---|---|
Day 1 | Day 5 | Day 10 | Day 20 | Day 35 | Day 40 (discharge) | 40 days after discharge | ||
White blood cell count (×109/L) | 3.5–9.5 | 13.05 | 10.07 | 17.77 | 23.85 | 7.42 | 6.94 | 5.36 |
Neutrophil (%) | 40–75 | 88.3 | 92.4 | 83.2 | 96.9 | 82.2 | 76.3 | 57.3 |
CD4 T cell count (cell/µL) | 471–1220 | 48 | – | – | 115 | – | 316 | 434 |
PCT (ng/mL) | 0–0.05 | 0.21 | 0.07 | 0.1 | 0.61 | 0.11 | 0.05 | – |
PaO2/FiO2 ratio (mmHg) | 400–500 | 115 | 110 | 105 | 110 | 160 | 240 | 360 |
Etiological examination | NGS (BALF): Cryptococcus neoformans; serum cryptococcal antigen: positive; lung biopsy: cryptococcus | fungus culture of BALF: Cryptococcus neoformans, resistant to fluconazole | ||||||
Image | Figure 1a–c | Figure 1d, e | Figure 1f–h | |||||
Drugs | Moxifloxacin: 400 mg qd; methylprednisolone: 40 mg bid | Fluconazole: 600 mg qd; piperacillin-tazobactam: 4.5 g q 8 h | Flucytosine: 5 g qd PO; amphotericin B: 70 mg qd | Voriconazole: 200 mg bid PO | Voriconazole: 200 mg bid PO | |||
Respiratory support | Noninvasive ventilator | HFNC | nasal cannula | |||||