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Table 4 Laboratory and radiographic findings at hospital admission in all patients and by gender

From: Covid-19 and gender: lower rate but same mortality of severe disease in women—an observational study

 

N

All patients (N = 431)

Gender

Female (N = 119)

Male (N = 312)

p

Hemoglobin, g/L

417

134 [123–148]

127 [117–136]

139 [126–150]

 < 0.001

White blood cells, 109/L

417

6.25 [4.98–8.83]

5.92 [4.77–7.82]

6.44 [5.06–8.95]

0.10

Neutrophils, 109/L

376

4.74 [3.55–7.21]

4.52 [3.55–6.50]

4.87 [3.55–7.32]

0.50

Neutrophils, %

376

77.7 [70.5–84.7]

76.6 [69.7–84.2]

78.0 [71.3–84.8]

0.54

Lymphocytes, 109/L

263

0.89 [0.58–1.23]

0.89 [0.62–1.13]

0.90 [0.58–1.24]

0.68

Lymphocytes, %

263

14.0 [7.9–19.5]

14.6 [8.7–19.9]

13.9 [7.6–19.3]

0.56

Monocytes, %

263

6.1 [3.9–8.1]

5.2 [3.2–7.9]

6.2 [4.2–8.3]

0.048

Eosinophils, %

263

0.00 [0.00–0.30]

0.00 [0.00–0.30]

0.00 [0.00–0.30]

0.65

Basophils, %

263

0.20 [0.10–0.30]

0.20 [0.10–0.30]

0.20 [0.10–0.30]

0.75

Platelets, 109/L

407

179 [140–226]

209 [158–252]

171 [136–212]

 < 0.001

 ≥ 150—no. (%)

407

290 (71.3)

94 (83.9)

196 (66.4)

 < 0.001

INR, ratio

353

1.07 [1.02–1.16]

1.05 [1.01–1.12]

1.08 [1.02–1.16]

0.037

aPTT, ratio

338

1.15 [1.04–1.29]

1.09 [0.99–1.27]

1.17 [1.06–1.30]

0.024

AST, U/L

410

49.0 [35.0–74.0]

40.0 [29.0–55.0]

53.0 [38.0–84.0]

 < 0.001

ALT, U/L

412

37.0 [25.0–59.0]

30.0 [20.0–45.0]

40.0 [27.0–62.0]

 < 0.001

Total bilirubin, mg/dL

372

0.60 [0.50–0.90]

0.60 [0.40–0.80]

0.70 [0.50–0.90]

0.020

Creatinine, mg/dL

414

0.92 [0.77–1.23]

0.74 [0.61–0.91]

0.98 [0.84–1.35]

 < 0.001

Urea, mg/dL

354

45.0 [34.0–66.0]

38.0 [28.0–55.0]

48.0 [37.0–71.0]

 < 0.001

LDH, U/L

371

384 [300–516]

368 [291–484]

391 [308–529]

0.13

D-dimer, ng/mL

13

2337 [1587–6028]

4182 [1864–11437]

2067 [1463–3328]

0.32

Fibrinogen, g/L

94

0.61 [0.49–0.71]

0.53 [0.48–0.66]

0.63 [0.49–0.72]

0.19

CRP, mg/L

417

113 [56–16.2]

102 [48–145]

122 [58–165]

0.051

 ≥ 127—no. (%)

417

188 (45.1)

40 (35.4)

148 (48.7)

0.015

PCT, ng/mL

84

0.49 [0.12–1.90]

0.12 [0.05–1.00]

0.56 [0.21–2.35]

0.019

Na, mEq/L

414

138 [136–141]

138 [136–140]

138 [136–141]

0.86

K, mEq/L

412

3.9 [3.6–4.3]

3.8 [3.5–4.2]

4.0 [3.7–4.3]

0.028

Cl, mEq/L

289

102 [99–104]

101 [98–103]

102 [99–104]

0.46

Abnormalities at chest

X-ray—no. (%)

413

355 (86.0)

98 (87.5)

257 (85.4)

0.58

 Unilateral

413

77 (18.6)

17 (15.2)

60 (19.9)

0.27

 Bilateral

413

278 (67.3)

81 (72.3)

197 (65.4)

0.19

  1. Data expressed as median and IQR [Interquartile Range] (continuous variables) and as column percentages (categorical variables). Percentages may not total 100 because of rounding, Hemocromocytometric values data shown as Hemoglobin, White blood cells and Platelets count. INR = International Normalization Ratio for prothrombin time; aPTT = Activated Partial Thromboplastin Time; AST = Aspartate Aminotransferase; ALT = Alanine Aminotransferase; LDH = Lactate Dehydrogenase; D-dimer = Fibrin Degradation product; CRP = C-reactive Protein; PCT = Procalcitonin; Na = Sodium; K = Potassium; Cl = Chloride. p values obtained by Chi-square test (or Fisher's exact test when appropriate) for categorical variables and Wilcoxon-Mann- Whitney test for continuous variables