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Fig. 6 | BMC Pulmonary Medicine

Fig. 6

From: Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD

Fig. 6

Collagen deposition around the airway, as assessed using Masson’s trichrome staining. Six- to eight-week-old male C57BL/6 J mice were exposed to CS for 6 months or CS for 6 months and an intranasal instillation of LPS on days 1 and 14. a Lung morphology was assessed by performing Masson’s trichrome staining of lung sections. Original magnification: × 200, bar = 100 μm; collagen: blue; nuclei: black; cytoplasm/epithelia: red. b Quantification of Masson’s trichrome staining for the collagen content in mice from the control group (n = 6), CS group (n = 6) and CS + LPS group (n = 6). Data are presented as the means ± SD, N = 6; #P < 0.05; ##P < 0.01 for the comparison of the CS group with the control group; *P < 0.05; **P < 0.01; ***P < 0.001 for the comparison of the CS + LPS group with the control group; &P < 0.05; &&P < 0.01 for the comparison of the CS + LPS group with the CS group

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