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Table 2 The sensitivity, specificity, positive predictive values, and negative predictive values of the decision-tree analysis to distinguish five types of pleural effusion

From: A retrospective study on the combined biomarkers and ratios in serum and pleural fluid to distinguish the multiple types of pleural effusion

Target

Sensitivity (%) (95% CI)

Specificity (%) (95% CI)

PPV (95% CI)

NPV (95% CI)

TPE

100.0 (89.6–100.0)

98.7 (93.2–100.0)

97.1 (85.1–99.6)

100.0 (95.3–100.0)

MPE

80.0 (60.9–91.1)

87.4 (78.8–92.8)

64.5 (47.0–78.9)

93.8 (86.4–97.3)

CPPE

89.5 (68.6–97.1)

98.9 (94.2–99.8)

94.4 (74.2–99.0)

97.9 (92.6–99.4)

UPPE

66.7 (47.8–81.4)

96.5 (90.1–98.8)

85.7 (65.4–95.0)

90.1 (82.3–94.7)

PE caused by CTDs

87.5 (52.9–97.8)

99.0 (94.8–99.8)

87.5 (52.9–97.8)

99.0 (94.8–99.8)

  1. TPE tuberculous pleural effusion, MPE malignant pleural effusion, CPPE complicated parapneumonic effusion, UPPE uncomplicated parapneumonic effusion, CTDs connective tissue diseases, CI confidence interval, PPV positive predictive value, NPV negative predictive value