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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Nuclear factor-kappaB regulates the transcription of NADPH oxidase 1 in human alveolar epithelial cells

Fig. 2

NF-κB/p65 knockdown attenuated oxidative stress induced by TNF-α in A549. Control: A549 were cultured without siRNA or TNF-α. TNF-α: A549 were treated with TNF-α (10 ng/ml) 24 h in the absence of NF-κB/p65 siRNA. NF-κB/p65 siRNA + TNF-α: A549 were pre-transfected with NF-κB/p65 siRNA and then treated with TNF-α (10 ng/ml) 24 h. Scrambled siRNA + TNF-α: A549 were pre-transfected with Scrambled siRNA and then treated with TNF-α (10 ng/ml) 24 h. (A) ROS, (B) MDA, (C)T-AOC, (D) SOD and (E) tGSH. The values are reported as the Mean ± S.D. (n = 6 for each group). *P < 0.05, compared with Control; #P < 0.05, compared with TNF-α and Scrambled siRNA + TNF-α

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