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Table 3 Individual and joint association of smoking and PM2.5 with COPD among participants in this study

From: Joint association of cigarette smoking and PM2.5 with COPD among urban and rural adults in regional China

Exposure variables Prevalence of COPD among participants,% (n/N) OR (95%CI)
Smoking exposure Annual mean PM2.5 exposure Model 1a Model 2b
Non-smokers N/A 6.4 (132/2073) 1   1  
Smokers N/A 20.6 (275/1334) 2.64 (1.89, 3.68)   2.46 (1.76, 3.43)  
N/A < 75 μg/m3 10.9 (/2,462,267) 1   1  
N/A ≥ 75 μg/m3 14.1 (161/1140) 1.26 (1.01, 1.58)   1.29 (1.02, 1.64)  
Non-smokers < 75 μg/m3 6.3 (90/1420) 1   1  
Non-smokers ≥ 75 μg/m3 6.4 (42/653) 1.00 (0.67, 1.46)   1.10 (0.74, 1.64)  
Smokers < 75 μg/m3 18.4 (156/847) 2.29 (1.56, 3.37) 1 2.22 (1.51, 3.27) 1
Smokers ≥ 75 μg/m3 24.4 (119/487) 2.96 (2.04, 4.31) 1.43 (1.09, 1.88) c 3.14 (2.15, 4.59) 1.36 (1.01, 1.83)c
  1. Smoking exposure: −, Non-smoker; + , smoker
  2. Annual mean PM2.5 exposure: −, < 75 μg/m3; + , ≥ 75 μg/m3
  3. aModel 1 was a univariate analysis with smoking exposure or annual mean PM2.5 as main effects and study sites as random effects
  4. bModel 2 was a multivariate analysis with adjustment for age, gender, residence, education, occupation, biomass use, parental history of respiratory diseases,body weight status, annual mean PM2.5 exposure/cigarette smoking, in addition to Model 1
  5. cThe OR predicted the likelihood for smokers who exposed to PM2.5 ≥ 75 μg/m3 to experience COPD compared to their counterparts who exposed to PM2.5 < 75 μg/m3 in this study