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Table 4 Logistic regression model analysis of sputum cytology positive patients

From: Detection of EGFR mutation of pulmonary adenocarcinoma in sputum using droplet digital PCR

 

Univariate analysis

Multivariate analysis

OR

95% CI

p value

OR

95% CI

p value

Age (65 ≤)

0.70

0.21–2.31

0.560

   

Gender (male)

0.81

0.25–2.58

0.720

   

Smoking (current or ex-smoker)

2.52

0.53–12.0

0.246

   

Right side

0.55

0.56–1.89

0.342

   

Lobe (upper)

3.24

0.94–11.2

0.063

   

Emphysema

0.71

0.08–6.01

0.755

   

Interstitial pneumonia

8.67

0.51–148

0.136

   

CT tumor size (29 mm ≤)

12.5

2.63–59.9

0.002

10.6

1.85–61.0

0.008

PET SUVmax (3.1 ≤)

5.73

2.30–14.3

 < 0.001

4.54

0.43–48.4

0.211

Clinical stage (II ≤)

4.23

1.73–10.3

0.002

1.47

0.31–6.91

0.627

Pathological stage (II ≤)

6.09

2.49–14.9

 < 0.001

1.87

0.37–9.59

0.451

Lymphatic invasion

0.90

0.18–4.42

0.891

   

Vascular invasion

2.35

0.70–7.87

0.164

   

Pleural invasion

1.43

0.40–5.12

0.586

   

STAS

23.0

2.87–184

0.003

17.7

1.97–158

0.010

Ex19 or Ex21mutation

0.66

0.20–2.16

0.493

   
  1. PET, positron emission tomography; SUV, standard uptake value; STAS, spread through air spaces; EGFR, epidermal growth factor receptor; Ex19, exon 19 deletion mutation; Ex21, exon 21 L858R point mutation; OR, odds ratio; CI, confidence interval