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Table 2 Comparison of clinical, demographic characteristics and quality of life between patients with and without insomnia

From: Insomnia in adults with cystic fibrosis: strong association with anxiety/depression and impaired quality of life

 

Patients with insomnia (ISI > 7) (n = 12)

Patients without insomnia (ISI ≤ 7) (n = 16)

p

Age (years)

22 (18–26)

27 (22–33)

0.62

Sex (M/F)

6 (50%)/6 (50%)

12 (75%)/4 (25%)

0.24

BMI (kg/m2)

21 (20–25)

22 (20–26)

0.98

Anxiolytic (n = 27)

2 (17%)

0 (0%)

0.18

Screen time (h/day)

7 (5–8)

5 (4–8)

0.74

Coffee intake (cups/day)

0 (0–2)

1 (1–2)

0.36

Tea intake (cups/day)

0 (0–1)

1 (0–1)

0.41

Alcohol intake (g/day)

0 (0–1)

0 (0–3)

0.73

Shift work

0 (0%)

2 (13%)

0.49

Insomnia Severity Index

   

 ISI score

14 (13–18)

3 (3–5)

 < 0.0001

Pittsburgh Sleep Quality Index

   

 PSQI score

9 (7–12)

3 (3–4)

 < 0.0001

 PSQI > 5

11 (92%)

2 (13%)

 < 0.0001

Morningness-Eveningness Questionnaire

   

 MEQ score

49 (41–57)

55 (52–62)

0.03

 Morning type

2 (17%)

6 (38%)

0.40

 Neither type

6 (50%)

10 (62%)

0.70

 Evening type

4 (33%)

0 (0%)

0.02

Epworth Sleepiness scale

   

 ES score

5 (5–9)

5 (4–6)

0.55

 ES score > 10

1 (8%)

0 (0%)

0.43

Numeric rating scale for pain (n = 22)

3 (1–4)

0 (0–1)

 < 0.05

Berlin scale

   

 Berlin score

1 (0–2)

0 (0–1)

0.07

 Berlin > 1

4 (33%)

1 (6%)

0.13

Restless Legs Syndrome

5 (42%)

0 (0%)

 < 0.01

 IRLS score

0 (0–13)

0 (0–0)

 < 0.05

 0 ≤ IRLS score ≤ 10 (mild RLS)

0 (0%)

0 (0%)

1.00

 11 ≤ IRLS score ≤ 40 (moderate to very severe RLS)

5 (42%)

0 (0%)

 < 0.01

Hospital Anxiety Depression scale

   

 Anxiety HAD score

9 (8–11)

4 (3–6)

 < 0.0001

 Anxiety HAD score > 7

9 (75%)

1 (6%)

 < 0.001

 Depression HAD score

7 (5–10)

1 (1–4)

 < 0.001

 Depression HAD score > 7

5 (42%)

0 (0%)

 < 0.01

CFQ-R score

   

 Physical functioning

52 (29–79)

83 (75–92)

 < 0.05

 Vitality

42 (25–42)

67 (50–83)

 < 0.001

 Emotional functioning

64 (40–73)

93 (87–100)

 < 0.001

 Eating problems

89 (67–100)

100 (89–100)

0.20

 Treatment burden

67 (44–78)

78 (56–89)

0.24

 Health perception

56 (33–67)

67 (56–78)

 < 0.05

 Social functioning

61 (39–67)

83 (78–94)

 < 0.01

 Body image

56 (33–67)

78 (67–89)

 < 0.001

 Role limitations

71 (58–75)

92 (92–100)

 < 0.001

 Weight problems

67 (33–100)

67 (33–100)

0.98

 Respiratory symptoms

56 (56–78)

78 (67–94)

 < 0.05

 Digestive symptoms

78 (67–89)

89 (89–100)

 < 0.05

  1. Data are expressed as median (interquartile range) and as number (percentage) of patients
  2. ISI: Insomnia Severity Index, PSQI: Pittsburgh Sleep Quality Index, MEQ: Morningness-Eveningness Questionnaire, ES: Epworth Sleepiness Scale, RLS: Restless Legs Syndrome, IRLS: International Restless Legs Syndrome Scale, HAD: Hospital Anxiety and Depression scale. CFQ-R: Cystic Fibrosis Questionnaire-Revised