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Table 3 Comparison of respiratory assessment parameters between patients with and without insomnia

From: Insomnia in adults with cystic fibrosis: strong association with anxiety/depression and impaired quality of life

  Patients with insomnia (ISI score > 7) (n = 12) Patients without insomnia (ISI score ≤ 7) (n = 16) p
CASA-Q score 51 (35–70) 34 (29–40)  < 0.05
Nocturnal cough 7 (58%) 6 (38%) 1.00
mMRC score    
 ≥ 1 7 (58%) 8 (50%) 0.72
 ≥ 2 5 (42%) 0 (0%)  < 0.05
Nasal obstruction 6 (50%) 2 (13%) 0.09
Pulmonary exacerbations 1 (0–2) 1 (0–2) 0.64
 Number per year    
 Number over last 3 months 1 (0–1) 0 (0–1) 0.78
 At least 1 exacerbation in the past year 6 (50%) 10 (62%) 0.70
 At least 1 exacerbation in the past 3 months 6 (50%) 7 (44%) 1.00
 At least 1 antibiotic use in the past year 4 (33%) 2 (13%) 0.35
Bacterial colonization of the airways (n = 27)    
 Pseudomonas aeruginosa 3 (25%) 11(69%) 0.24
 Burkholderia cepacia 0 (0%) 0 (0%) 1.00
 Stenotrophomonas maltophilia 1 (8%) 0 (0%) 0.44
 Achromobacter xylosoxidans 0 (0%) 0 (0%) 1.00
Pulmonary function tests    
 FEV1 (mL) 2885 (1470–3490) 2065 (1540–4030) 0.93
 FEV1 (% predicted) 74 (40–108) 66 (38–89) 0.42
 FVC (mL) 3945 (2720–4435) 3530 (2680–5100) 1.00
 FVC (% predicted) 97 (65–113) 86 (65–97) 0.22
 FEV1/FVC 64 (55–82) 69 (53–74) 0.70
6 MWT (n = 16)    
 SpO2 min (%) 93 (91–96) 96 (93–97) 0.25
 Distance (m) 496 (425–584) 581 (505–630) 0.21
  1. Data are expressed as median (interquartile range) and as number (percentage) of patients
  2. CASA-Q: Cough And Sputum Assessment, mMRC: modified Medical Research Council, FEV1: forced expiratory volume in 1 s, FVC: forced vital capacity, 6 MWT: 6-min walking test, SpO2: pulse oxygen saturation
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