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Table 3 Comparison of respiratory assessment parameters between patients with and without insomnia

From: Insomnia in adults with cystic fibrosis: strong association with anxiety/depression and impaired quality of life

 

Patients with insomnia (ISI score > 7) (n = 12)

Patients without insomnia (ISI score ≤ 7) (n = 16)

p

CASA-Q score

51 (35–70)

34 (29–40)

 < 0.05

Nocturnal cough

7 (58%)

6 (38%)

1.00

mMRC score

   

 ≥ 1

7 (58%)

8 (50%)

0.72

 ≥ 2

5 (42%)

0 (0%)

 < 0.05

Nasal obstruction

6 (50%)

2 (13%)

0.09

Pulmonary exacerbations

1 (0–2)

1 (0–2)

0.64

 Number per year

   

 Number over last 3 months

1 (0–1)

0 (0–1)

0.78

 At least 1 exacerbation in the past year

6 (50%)

10 (62%)

0.70

 At least 1 exacerbation in the past 3 months

6 (50%)

7 (44%)

1.00

 At least 1 antibiotic use in the past year

4 (33%)

2 (13%)

0.35

Bacterial colonization of the airways (n = 27)

   

 Pseudomonas aeruginosa

3 (25%)

11(69%)

0.24

 Burkholderia cepacia

0 (0%)

0 (0%)

1.00

 Stenotrophomonas maltophilia

1 (8%)

0 (0%)

0.44

 Achromobacter xylosoxidans

0 (0%)

0 (0%)

1.00

Pulmonary function tests

   

 FEV1 (mL)

2885 (1470–3490)

2065 (1540–4030)

0.93

 FEV1 (% predicted)

74 (40–108)

66 (38–89)

0.42

 FVC (mL)

3945 (2720–4435)

3530 (2680–5100)

1.00

 FVC (% predicted)

97 (65–113)

86 (65–97)

0.22

 FEV1/FVC

64 (55–82)

69 (53–74)

0.70

6 MWT (n = 16)

   

 SpO2 min (%)

93 (91–96)

96 (93–97)

0.25

 Distance (m)

496 (425–584)

581 (505–630)

0.21

  1. Data are expressed as median (interquartile range) and as number (percentage) of patients
  2. CASA-Q: Cough And Sputum Assessment, mMRC: modified Medical Research Council, FEV1: forced expiratory volume in 1 s, FVC: forced vital capacity, 6 MWT: 6-min walking test, SpO2: pulse oxygen saturation