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Table 4 Comparison of polysomnographic data between patients with and without insomnia

From: Insomnia in adults with cystic fibrosis: strong association with anxiety/depression and impaired quality of life

  Patients with insomnia (ISI score > 7) (n = 8) Patients without insomnia (ISI score ≤ 7) (n = 6) P
Sleep Latency (min) 26 (16–29) 19 (11–25) 0.57
Sleep latency > 45 min 1 (13%) 1 (17%) 1.00
Total Sleep Time (min) 415 (343–500) 453 (441–526) 0.35
 N1 (min) 16 (8–21) 10 (8–15) 0.57
 N1 (% TST) 4 (2–5) 2 (2–3) 0.32
 N2 (min) 242 (182–274) 195 (183–234) 0.57
 N2 (% TST) 51 (44–57) 45 (40–52) 0.29
 N3 (min) 80 (72–118) 124 (95–145) 0.16
 N3 (% TST) 21 (15–26) 26 (21–32) 0.42
 REM (min) 87 (65–112) 119 (112–164) 0.13
 REM (% TST) 22 (18–23) 27 (25–30) 0.05
Sleep Efficiency (%) 88 (86–92) 94 (88–96) 0.18
Arousal index (/h) 11 (6–14) 8 (5–12) 0.35
Wake after sleep onset (min) 60 (35–109) 37 (28–81) 0.66
PLM (/h) 0 (0–0) 0 (0–0) 1.00
PLM > 15/h 0 (0%) 0 (0%) 1.00
Apnea–Hypopnea Index (/h) 0 (0–2) 1 (0–4) 0.85
Mean SpO2 during sleep (%) 92 (92–94) 96 (94–96)  < 0.05
% SpO2 < 90% asleep 0 (0–3) 0 (0–0) 0.53
Oxygen Desaturation Index (3%) (/h) 3 (2–7) 4 (3–6) 0.45
Mean PtcCO2 during sleep (mmHg) 45 (41–46) 46 (43–47) 0.25
Max PtcCO2 during sleep (mmHg) 47 (44–50) 50 (47–51) 0.59
% PtcCO2 > 50 mmHg 0 (0–2) 0 (0–2) 1.00
  1. Data are expressed as median (interquartile range) and as number (percentage) of patients
  2. REM: rapid eye movement sleep, PLM: periodic leg movements, SpO2: pulse oxygen saturation, PtcCO2: transcutaneous carbon dioxide pressure
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