Table 1 Review of the previous cases of pulmonary complication for intravesical BCG treatment
Total cases | n = 39 |
|---|---|
Male (sex was not described in 5 cases) | 34 (97) |
Age, year | 68 (64–75) |
Smoker | 7 (18) |
Diabetes mellitus | 3 (8) |
Alcohol abuse | 1 (3) |
Malignancy | 3 (8) |
HIV infection | 1 (3) |
COPD | 4 (10) |
Asthma | 1 (3) |
Interstitial pneumonia | 1 (3) |
Old pulmonary tuberculosis | 4 (10) |
Ischemic heart disease | 4 (10) |
BPH | 3 (8) |
Bladder cancer treatment | |
|---|---|
Only BCG therapy | 21 (54) |
BCG + Mitomycin C | 1 (3) |
TURBT + BCG (± Mitomycin C) | 15 (38) |
Cystectomy (± TURBT) + BCG | 2 (5) |
BCG therapy before onset, times | 6 (5–9) |
Time from final BCG injection to onset, day | 30 (7–154) |
Chest CT findings | |
|---|---|
Miliary pattern (diffused well-defined small nodular opacity) | 22 (56) |
Diffused ill-defined small nodular opacity | 3 (8) |
Multiple nodules | 1 (3) |
Grand glass opacity | 7 (18) |
Consolidation | 9 (23) |
Interlobular septae thickening | 1 (3) |
Bronchial wall thickening | 1 (3) |
Pleural effusion | 5 (13) |
Mediastinal and/or hilar lymphadenopathy | 3 (8) |