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Table 1. Demographic and clinical characteristics of moderate patients with COVID-19

From: Risk stratification scores for hospitalization duration and disease progression in moderate and severe patients with COVID-19

 

Total

(n = 1681)

Length of hospital stays

p-value

Short-stay (≤ 13 days)

(n = 892)

Long-stay (> 13 days)

(n = 789)

Age (years)

58 (48,67)

56 (46, 65)

61 (50, 68)

<0.001

 ≥ 60

786 (46.8%)

370 (41.5%)

416 (52.7%)

<0.001

Gender

 Male

836 (49.7%)

441 (49.4%)

395 (50.1%)

0.799

 Female

845 (50.3%)

451 (50.6%)

394 (49.9%)

 

History of smoking

 Yes

115/1662 (6.9%)

66/885 (7.5%)

49/777 (6.3%)

0.356

Clinical symptoms

 Cough

1182 (70.3%)

584 (65.5%)

598 (75.8%)

<0.001

 Fever

1216 (72.3%)

585 (65.6%)

631 (80.0%)

<0.001

 Asthma or dyspnea

702 (41.8%)

311 (34.9%)

391 (49.6%)

<0.001

 Fatigue

898 (53.4%)

430 (48.2%)

468 (59.3%)

<0.001

 Myalgia

500 (29.7%)

217 (24.3%)

283 (35.9%)

<0.001

 Other features

464 (27.6%)

235 (26.3%)

229 (29.0%)

0.220

Clinical outcome

 Discharge

1675 (99.6%)

890 (99.8%)

785 (99.5%)

0.332

 Died

6 (0.4%)

2 (0.2%)

4 (0.5%)

 

Number of symptoms

3 (2, 4)

3 (2, 4)

3 (2, 5)

<0.001

 > 3

644 (38.3%)

272 (30.5%)

372 (47.1%)

<0.001

Maximum body temperature ≥ 37.3 ℃

502/1664 (30.2%)

167/884 (18.9%)

335/780 (42.9%)

<0.001

Comorbidity

 Hypertension

467/1672 (27.9%)

240/891 (26.9%)

227/781 (29.1%)

0.333

 Diabetes

214/1672 (12.8%)

109/891 (12.2%)

105/781 (13.4%)

0.460

 Other cardiovascular disease

159/1672 (9.5%)

86/891 (9.7%)

73/781 (9.3%)

0.832

 Respiratory disease

84/1672 (5.0%)

51/891 (5.7%)

33/781 (4.2%)

0.162

 Other disease

243/1672 (14.5%)

118/891 (13.2%)

125/781 (16.0%)

0.110

Imaging features

Position

 Bilateral pulmonary

1375/1512 (90.9%)

699/791 (88.4%)

676/721 (93.8%)

<0.001

Density

 mGGO

1269/1487 (85.3%)

643/749 (85.8%)

626/738 (84.8%)

0.577

Therapy

 Antibiotics

441/1670 (26.4%)

149/887 (16.8%)

292/783 (37.3%)

<0.001

 Antiviral

776/1674 (46.4%)

288/890 (32.4%)

488/784 (62.2%)

<0.001

 Corticosteroids

105/1652 (6.4%)

16/884 (1.8%)

89/768 (11.6%)

<0.001

 Traditional Chinese medicine treatment

1522/1669 (91.2%)

771/888 (86.8%)

751/781 (96.2%)

<0.001

Oxygen therapy

998/1641 (60.8%)

475/881 (53.9%)

523/760 (68.8%)

<0.001

Other therapy

109/1622 (6.7%)

32/871 (3.7%)

77/751 (10.3%)

<0.001

Laboratory findings

 Leucocyte count, ×109 per L

5.60 (4.70, 6.80)

5.60 (4.80, 6.80)

5.50 (4.50, 6.90)

0.103

 Lymphocyte count, ×109 per L

1.56 (1.19, 1.92)

1.65 (1.30, 2.02)

1.43 (1.07, 1.81)

<0.001

 Hemoglobin, g/L

125 (115, 136)

127 (116, 136)

123 (114, 134)

<0.001

 Platelet count, × 109 per L

226 (186, 279)

215 (181, 261)

241 (193, 305)

<0.001

 NLR

2.18 (1.62, 3.01)

2.02 (1.58, 2.73)

2.39 (1.69, 3.42)

<0.001

 CRP, mg/L

1.71 (0.68, 5.12)

1.22 (0.55, 3.03)

2.68 (0.91, 9.31)

<0.001

 ALT, U/L

23.40 (14.60, 38.70)

21.20 (14.10, 33.78)

25.95 (15.80, 42.70)

<0.001

 Albumin, g/L

38.30 (35.60, 40.63)

39.40 (36.90, 41.50)

36.90 (34.10, 39.50)

<0.001

 BUN, mmol/L

4.32 (3.59, 5.22)

4.34 (3.61, 5.33)

4.27 (3.59, 5.15)

0.203

 Creatinine, umol/L

64.00 (55.00,74.90)

63.90 (54.90, 75.00)

64.10 (55.00, 74.50)

0.941

 Creatine kinase, U/L

50.10 (36.00, 71.25)

53.75 (38.85, 72.50)

45.20 (32.40, 67.40)

<0.001

 LDH, U/L

170.30 (148.50, 201.20)

161.60 (142.50, 186.70)

185.20 (159.45, 228.95)

<0.001

 Prothrombin time, s

12.72 (12.18, 13.40)

12.74 (12.23, 13.40)

12.71 (12.13, 13.40)

0.756

 D-dimer, ug/L

0.35 (0.18, 0.64)

0.30 (0.17, 0.56)

0.41 (0.23, 0.82)

<0.001

  1. Values are median (interquartile range) or number (percentage). P-values were calculated by Mann–Whitney U test or χ2 test, and bold represents significant differences between subgroups. COVID-19, coronavirus disease 2019; mGGO, mixed ground glass opacity; WBC, white blood cell; NLR, neutrophil-to-lymphocyte ratio; CRP, C reaction protein; ALT, alanine aminotransferase; BUN, blood urea nitrogen; LDH, lactate dehydrogenase