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Table 4 Comparison of comorbidities in selected studies

From: Monotherapy in patients with pulmonary arterial hypertension at four German PH centres

Comorbidity

Current study

Study 1 (12)

Study 2 (30)

Study 3 (23)

No. of patients

131

264

237

1247

BMI (kg/m2)

28.1 ± 6.4

27.5 ± 5.5

29.6 ± 8.3

n.a

Arterial hypertension

72.5

51

30

38.9

Diabetes mellitus

29

29

17.7

10.2

Ischaemic stroke

n.a

7

n.a

n.a

Ischaemic heart disease

24.4

18

40.9

8.9

Atrial fibrillation

28.4

17

n.a

n.a

Obesity

29.8

21

n.a

28.6

Chronic kidney disease

48.9

51

15.6

4.8

COPD

22.9

n.a

19.8

21.1

OSA

9.2

n.a

19

15.9

Depression

n.a

n.a

n.a

25.3

Thrombosis, pulmonary embolism

14.5

n.a

n.a

11.9

Diastolic dysfunction by echocardiography

47.3

n.a

n.a

n.a

Thyroid disease

22.9

n.a

n.a

23.2

Cancer

8.4

n.a

n.a

5.9

Peripheral arterial occlusive disease

4.6

n.a

n.a

n.a

  1. Continuous data are expressed as the mean (± SD); nominal data are given as percentages