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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: A systematic review of the incidence, risk factors and prognosis of acute exacerbation of systemic autoimmune disease-associated interstitial lung disease

Fig. 1

Study flow diagram. A total of 2662 reports were identified through Medline, EMBASE, Science Citation Index Expanded and Google Scholar. After excluding 663 duplicates, 8 non-English records, 1125 reports of ineligible types (consisting of 480 conference proceedings, 361 review articles, 84 editorials or letters and 200 case reports) and 805 irrelevant articles, the remaining 61 reports were obtained as full-texts. Out of these, 37 reports were excluded due to neither risk nor prognosis in 5 studies, rapidly progressive interstitial lung disease in one article, acute respiratory failure not specified as acute exacerbation in 22 studies, no description of systemic autoimmune disease in 6 studies and traditional reviews in 3 studies. Finally, 24 studies were eligible for this review. Of these, seven studies were excluded from risk of bias assessment and the analysis of risk or prognostic factors because no such information was available. The remaining 17 studies were analysed in more details to elucidate risk and/or prognostic factors of acute exacerbation of systemic autoimmune disease-associated interstitial lung disease

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