| |
Derivation cohort (n = 2237)
|
Validation cohort (n = 746)
|
P value
|
|---|
|
Mean
|
SD
|
Mean
|
SD
|
|---|
|
Age (years)
|
24.20
|
3.67
|
24.20
|
3.60
|
0.62
|
|
Females
|
434 (19%)
|
–
|
142 (19%)
| |
0.83*
|
|
Height (cm)
|
173.53
|
8.42
|
173.87
|
8.50
|
0.34
|
|
Weight (kg)
|
69.43
|
12.45
|
69.40
|
12.70
|
0.96
|
|
BMI (kg/m2)
|
22.99
|
3.44
|
22.92
|
3.70
|
0.67
|
|
FEV1/FVC (%pred)
|
83.50
|
7.50
|
83.40
|
7.20
|
0.61
|
|
FEV1 (%pred)
|
94.50
|
11.30
|
94.40
|
11.30
|
0.92
|
|
FEF50% (%pred)
|
87.80
|
22.80
|
87.60
|
22.30
|
0.82
|
|
FVC (%pred)
|
99.10
|
13.00
|
99.50
|
13.20
|
0.49
|
|
FEF25–75% (%pred)
|
86.30
|
23.10
|
87.10
|
23.70
|
0.43
|
|
PC20 ≤ 16 mg/ml (%)
|
305 (14%)
|
–
|
103 (14%)
| |
0.91*
|
|
Angle β (°)
|
186.14
|
14.80
|
185.88
|
14.80
|
0.68
|
- BMI, Body Mass Index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; FEF50%, forced expiratory flow at 50% of FVC; FEF25–75%, forced expiratory flow at 25–75% of FVC; PC20, Concentration of methacholine causing a 20% decrease in FEV1. Relative values of spirometry parameters are given as percentage of the predicted value (% pred)
- *P value from Chi-squared analysis
