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Table 2 Prognosis analysis for severe AECOPD

From: Prognostic marker for severe acute exacerbation of chronic obstructive pulmonary disease: analysis of diffusing capacity of the lung for carbon monoxide (DLCO) and forced expiratory volume in one second (FEV1)

Parameter

Univariate analysis

Multivariate analysis

DLCO normal group (DLCO > 50, n = 227)

DLCO impaired group (DLCO ≤ 50, n = 115)

P value

Odds ratio

95% CI

P value

Mortality in hospital‡

3 (1.3%)

8 (7.0%)

0.008

4.408

1.070–18.167

0.040

Mechanical ventilation‡

11 (4.8%)

19 (15.7%)

0.001

2.855

1.216–6.704

0.016

Intensive care unit‡

16 (7.0%)

23 (20.0%)

< 0.001

2.685

1.290–5.590

0.008

 

FEV1 normal group (FEV1 > 50, n = 173)

FEV1 impaired group (FEV1 ≤ 50, n = 169)

    

Mortality in hospital‡

3 (1.7%)

8 (4.7%)

0.116

4.633

0.858–25.036

0.075

Mechanical ventilation‡

7 (4.0%)

22 (13.0%)

0.003

3.518

1.335–9.270

0.011

Intensive care unit‡

9 (5.2%)

30 (17.8%)

< 0.001

4.527

1.886–10.869

0.001

  1. Multivariate analysis was conducted for variables with a P value of less than 0.05 in the univariate analysis, except for baseline spirometry
  2. AECOPD acute exacerbations of chronic obstructive pulmonary disease, FEV1 forced expiratory volume in one second, DLCO diffusing capacity of the lung for carbon monoxide
  3. †Numbers are presented as mean ± standard deviation
  4. ‡Numbers are presented as n (%)
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BMC Pulmonary Medicine

ISSN: 1471-2466

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