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Table 1 Demographics of asbestosis, silicosis and healthy controls

From: Downregulation of the PD-1/PD-Ls pathway in peripheral cells correlates with asbestosis severity

  Asbestosis Silicosis Controls P value*
Subjects 30 23 25
Age, years 71.3 ± 8.7 52.9 ± 12.0 46.8 ± 5.4 0.000
Female/male, n 17/13 14/9 7/18 0.040
Smoker/non-smoker,n 12/18 4/19 13/12 0.043
PaO2, mmHg 77.63 ± 11.73 79.94 ± 14.12 87.92 ± 2.69 0.041
FVC, %pred 61.18 ± 23.30 88.87 ± 22.36 89.16 ± 2. 54 0.000
FEV1, %pred 59.74 ± 24.15 70.47 ± 27.59 89.80 ± 8.45 0.000
FEV1/FVC, % 75.81 ± 10.90 67.07 ± 16.55 87.24 ± 2.82 0.000
TLC, %pred 74.07 ± 20.87 83.02 ± 31.25 90.52 ± 3.02 0.290
DLCO, %pred 55.86 ± 25.93 76.47 ± 17.96 85.84 ± 3.24 0.000
  1. Data are presented as Means ± SD.*: P value denotes statistical differences among three groups; PaO2, the arterial partial pressure of oxygen; FVC, forced vital capacity; FEV1, forced expiratory volume in the first second; TLC, total lung capacity; DLCO, diffusing capacity of the lung for carbon monoxide