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Table 3 Levels of evidence

From: Guidelines on analgosedation, monitoring, and recovery time for flexible bronchoscopy: a systematic review

Level of evidence

ILATF

BTS

IAB

JICS

High Evidence

GRADE A: requires at least one randomized control trial as part of a body of literature of overall good quality and consistency addressing the specific recommendation

GRADE A/B | 1 +  + and 1 + 

Level 1: High‐quality evidence supported by findings from well‐executed randomized controlled trials or unequivocal evidence from well‐conducted observational studies with strong effects”

"Level 1: High‐quality evidence supported by findings from well‐executed randomized controlled trials or unequivocal evidence from well‐conducted observational studies with strong effects "

Moderate Evidence

Grade B: requires availability of well-conducted clinical studies but no randomized clinical trials on the topic of the recommendation

GRADE C/D | 1-/2 + /2 +  + 

Level 2: Moderate‐quality evidence from randomized trials or from several observational studies with some limitations (inconsistency, indirectness, flaws in conduct, reporting bias, imprecise estimates, small sample size, or others)

Level 2: Moderate‐quality evidence from randomized trials or from several observational studies with some limitations (inconsistency, indirectness, flaws in conduct, reporting bias, imprecise estimates, small sample size, or others)

Low Evidence

"Grade C: requires evidence from expert committee reports or opinions and clinical experience of respected authorities."

Important practice point | 3 and 4

"Level 3: Low‐quality evidence from observational studies or from controlled trials with serious limitations UPP: Not supported by sufficient evidence; however, a consensus reached by the working group, based on clinical experience and expertise "

"Level 3: Low‐quality evidence from observational studies or from controlled trials with serious limitations UPP: Not supported by sufficient evidence; however, a consensus reached by the working group, based on clinical experience and expertise "