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Table 4 Conventional logistic model using data of the training cohort: RMPP-5

From: Prediction model for prolonged fever in patients with Mycoplasma pneumoniae pneumonia: a retrospective study of 716 pediatric patients

  Univariate Multivariate
Odds ratio 95% confidence interval p-value Odds ratio 95% confidence interval p-value
Age (years) 1.046 (0.963, 1.138) 0.287    
Sex (female: male) 0.500 (0.292, 0.857) 0.012    
WBC × 103/µL 1.000 (1.000, 1.000) 0.017    
Neutrophils (%) 1.046 (1.022, 1.071) < 0.001    
Absolute neutrophil count × 103/µL 1.000 (1.000, 1.000) 0.292    
Lymphocytes (%) 0.951 (0.924, 0.978) < 0.001    
Absolute lymphocyte count × 103/µL 0.999 (0.998, 0.999) < 0.001    
Hemoglobin (g/dL) 0.950 (0.713, 1.266) 0.728    
Platelet × 103/µL 0.982 (0.977, 0.987) < 0.001    
ESR (mm/hr) 0.994 (0.979, 1.008) 0.391    
CRP (mg/L) 1.015 (1.010, 1.021) < 0.001    
Procalcitonin (ng/mL) 1.056 (0.895, 1.245) 0.518    
LDH (IU/L) 1.004 (1.002, 1.006) 0.001    
AST (IU/L) 1.003 (0.997, 1.009) 0.355    
ALT (IU/L) 0.996 (0.986, 1.006) 0.420    
Concurrent respiratory virus 0.624 (0.323, 1.207) 0.161    
Oxygen requirement 3.111 (0.930, 10.412) 0.066    
Radiologic grouping    < 0.001    0.007
 Group 1
 Group 2 3.464 (0.998, 12.020) < 0.001 1.693 (0.447, 6.403) 0.438
 Group 3 9.778 (2.919, 32.757) < 0.001 3.457 (0.942, 12.681) 0.061
 Group 4 102.667 (20.318, 518.780) < 0.001 13.947 (2.260, 86.077) 0.005
Pleural effusion 4.884 (2.578, 9.252) < 0.001    
Fever profiles       
 Highest temperature (°C) 5.424 (3.501, 8.403) < 0.001    
 Lowest temperature (°C) 54.127 (19.031, 153.945) < 0.001 6.494 (2.102, 20.068) 0.001
 Frequency of fever of > 39 °C within 48 h (n) 1.691 (1.494, 1.914) < 0.001    
 Frequency of fever of > 40 °C within 48 h (n) 3.230 (2.073, 5.033) < 0.001    
 Frequency of peak fever within 24 h (n) 2.676 (2.097, 3.413) < 0.001    
 Frequency of peak fever within 48 h (n) 1.872 (1.620, 2.162) < 0.001 1.603 (1.361, 1.887) 0.001
12 sequential body temperatures       
 Initial (°C) 2.017 (1.532, 2.654) < 0.001    
 After 4 h (°C) 1.988 (1.467, 2.695) < 0.001    
 After 8 h (°C) 1.852 (1.386, 2.474) < 0.001    
 After 12 h (°C) 1.960 (1.471, 2.610) < 0.001    
 After 16 h (°C) 2.134 (1.606, 2.834) < 0.001    
 After 20 h (°C) 3.740 (2.611, 5.358) < 0.001    
 After 24 h (°C) 3.138 (2.158, 4.562) < 0.001    
 After 28 h (°C) 2.926 (2.142, 3.996) < 0.001    
 After 32 h (°C) 1.930 (1.425, 2.615) < 0.001    
 After 36 h (°C) 2.929 (2.122, 4.043) < 0.001    
 After 40 h (°C) 3.446 (2.419, 4.908) < 0.001    
 After 44 h (°C) 3.873 (2.720, 5.515) < 0.001    
  1. RMPP-5 Refractory Mycoplasma pneumoniae pneumonia with fever for ≥ 120 h, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, LDH Lactate dehydrogenase, AST Aspartate aminotransferase, ALT Alanine aminotransferase