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Table 4 Conventional logistic model using data of the training cohort: RMPP-5

From: Prediction model for prolonged fever in patients with Mycoplasma pneumoniae pneumonia: a retrospective study of 716 pediatric patients

 

Univariate

Multivariate

Odds ratio

95% confidence interval

p-value

Odds ratio

95% confidence interval

p-value

Age (years)

1.046

(0.963, 1.138)

0.287

   

Sex (female: male)

0.500

(0.292, 0.857)

0.012

   

WBC × 103/µL

1.000

(1.000, 1.000)

0.017

   

Neutrophils (%)

1.046

(1.022, 1.071)

< 0.001

   

Absolute neutrophil count × 103/µL

1.000

(1.000, 1.000)

0.292

   

Lymphocytes (%)

0.951

(0.924, 0.978)

< 0.001

   

Absolute lymphocyte count × 103/µL

0.999

(0.998, 0.999)

< 0.001

   

Hemoglobin (g/dL)

0.950

(0.713, 1.266)

0.728

   

Platelet × 103/µL

0.982

(0.977, 0.987)

< 0.001

   

ESR (mm/hr)

0.994

(0.979, 1.008)

0.391

   

CRP (mg/L)

1.015

(1.010, 1.021)

< 0.001

   

Procalcitonin (ng/mL)

1.056

(0.895, 1.245)

0.518

   

LDH (IU/L)

1.004

(1.002, 1.006)

0.001

   

AST (IU/L)

1.003

(0.997, 1.009)

0.355

   

ALT (IU/L)

0.996

(0.986, 1.006)

0.420

   

Concurrent respiratory virus

0.624

(0.323, 1.207)

0.161

   

Oxygen requirement

3.111

(0.930, 10.412)

0.066

   

Radiologic grouping

  

< 0.001

  

0.007

 Group 1

 Group 2

3.464

(0.998, 12.020)

< 0.001

1.693

(0.447, 6.403)

0.438

 Group 3

9.778

(2.919, 32.757)

< 0.001

3.457

(0.942, 12.681)

0.061

 Group 4

102.667

(20.318, 518.780)

< 0.001

13.947

(2.260, 86.077)

0.005

Pleural effusion

4.884

(2.578, 9.252)

< 0.001

   

Fever profiles

      

 Highest temperature (°C)

5.424

(3.501, 8.403)

< 0.001

   

 Lowest temperature (°C)

54.127

(19.031, 153.945)

< 0.001

6.494

(2.102, 20.068)

0.001

 Frequency of fever of > 39 °C within 48 h (n)

1.691

(1.494, 1.914)

< 0.001

   

 Frequency of fever of > 40 °C within 48 h (n)

3.230

(2.073, 5.033)

< 0.001

   

 Frequency of peak fever within 24 h (n)

2.676

(2.097, 3.413)

< 0.001

   

 Frequency of peak fever within 48 h (n)

1.872

(1.620, 2.162)

< 0.001

1.603

(1.361, 1.887)

0.001

12 sequential body temperatures

      

 Initial (°C)

2.017

(1.532, 2.654)

< 0.001

   

 After 4 h (°C)

1.988

(1.467, 2.695)

< 0.001

   

 After 8 h (°C)

1.852

(1.386, 2.474)

< 0.001

   

 After 12 h (°C)

1.960

(1.471, 2.610)

< 0.001

   

 After 16 h (°C)

2.134

(1.606, 2.834)

< 0.001

   

 After 20 h (°C)

3.740

(2.611, 5.358)

< 0.001

   

 After 24 h (°C)

3.138

(2.158, 4.562)

< 0.001

   

 After 28 h (°C)

2.926

(2.142, 3.996)

< 0.001

   

 After 32 h (°C)

1.930

(1.425, 2.615)

< 0.001

   

 After 36 h (°C)

2.929

(2.122, 4.043)

< 0.001

   

 After 40 h (°C)

3.446

(2.419, 4.908)

< 0.001

   

 After 44 h (°C)

3.873

(2.720, 5.515)

< 0.001

   
  1. RMPP-5 Refractory Mycoplasma pneumoniae pneumonia with fever for ≥ 120 h, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, LDH Lactate dehydrogenase, AST Aspartate aminotransferase, ALT Alanine aminotransferase