Table 4 Univariate and multivariate analysis of favorable factors for postoperative prognosis in patients with moderate to severe AFL
Clinicopathologic variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
RR | 95%CI | p value | RR | 95%CI | p value | |
A. Analysis of favorable factors for overall survival | ||||||
Age (< 75 year) | 0.88 | 0.29–2.25 | 0.798 | – | – | – |
Histology: | 0.083 | – | – | – | ||
Squamous cell carcinoma | 1.00 | Reference | – | – | – | |
Adenocarcinoma | 0.47 | 0.18–1.14 | 0.094 | – | – | – |
Other | 0.18 | 0.01–1.01 | 0.051 | – | – | – |
Lymph node metastasis (absent) | 0.61 | 0.26–1.55 | 0.290 | – | – | – |
Pathologic stage: | 0.027 | 0.106 | ||||
I | 1.00 | Reference | 1.00 | Reference | ||
II | 2.96 | 0.99–8.25 | 0.052 | 2.14 | 0.70–6.16 | 0.176 |
III | 3.66 | 1.20–10.49 | 0.024 | 3.11 | 1.00–9.13 | 0.107 |
Bronchodilator | 0.010 | 0.048 | ||||
LAMA/LABA | 1.00 | Reference | 1.00 | Reference | ||
LAMA or No-BD | 4.16 | 1.37–11.1 | 3.21 | 1.01–14.20 | ||
B. Analysis of favorable factors for disease-free survival | ||||||
Age (< 75 year) | 0.59 | 0.69–5.12 | 0.266 | – | – | – |
Histology: | 0.038 | 0.350 | ||||
Squamous cell carcinoma | 1.00 | Reference | 1.00 | Reference | ||
Adenocarcinoma | 0.42 | 0.17–0.96 | 0.040 | 0.68 | 0.23–2.05 | 0.311 |
Other | 0.16 | 0.01–0.90 | 0.035 | 0.23 | 0.01–1.59 | 0.148 |
Lymph node metastasis (absent) | 0.49 | 0.22–1.13 | 0.091 | – | – | – |
Pathologic stage | 0.007 | 0.233 | ||||
I | 1.00 | Reference | 1.00 | Reference | ||
II | 3.21 | 1.18–8.17 | 0.024 | 1.35 | 0.39–4.90 | 0.635 |
III | 4.13 | 1.47–11.0 | 0.009 | 2.70 | 0.83–8.37 | 0.278 |
Bronchodilator | 0.003 | 0.018 | ||||
LAMA/LABA | 1.00 | Reference | 1.00 | Reference | ||
LAMA or No-BD | 3.90 | 1.55–11.8 | 3.29 | 1.22–10.43 | 0.120 | |