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Table 1 Modes and settings of mechanical ventilation and corresponding arterial blood gases (ABG)

From: Time controlled adaptive ventilation™ as conservative treatment of destroyed lung: an alternative to lung transplantation

 

Mode

FiO2/Vti

Pressures (cm H2O)

ABG; pressures in kPa

Admission to ICU at EMC (November 16th)

APRV + VV-ECMO

80% / 2.33 cc/kg

7L FiO2 1.0 sweep gas flow

Ppeak 41

Pplat 40

Pmean 28

pH 7.45

pO2 6.8

pCO2 5.7

November 17th

APRV + VV-ECMO

70% / 2.36 cc/kg

7L FiO2 1.0 sweep gas flow

Ppeak 44

Pplat 42

Pmean 28

pH 7.49

pO2 11.3

pCO2 5.0

December 20th

APRV + VV-ECMO

40% / 2.72 cc/kg

7.5L FiO2 1.0 sweep gas flow

Ppeak 36

Pplat 32

Pmean 23

pH 7.44

pO2 10.3

pCO2 6.6

January 12th

PS + VV-ECMO

30% / 4.34 cc/kg

4L FiO2 1.0 sweep gas flow

Ppeak 30

Pmean 13

PEEP 10

pH 7.38

pO2 11.0

pCO2 8.1

February 25th

No mechanical ventilation, no ECMO

0.5 L O2 nasal cannula

n.a

No ABG

Following surgery and repeat tracheostomy (April 24th)

Start APRV, no ECMO

35% / 4.36 cc/kg

Ppeak 34

Pmean 21

PEEP 11

pH 7.12

pO2 11.2

pCO2 10.5

April 29th

APRV, no ECMO

40%/4.08 cc/kg

Ppeak 31

Pplat 28

Pmean 23

pH 7.23

pO2 11.4

pCO2 9.9

May 5th

APRV, no ECMO

30%/3.44 cc/kg

Ppeak 21

Pplat 20

Pmean 17

pH 7.41

pO2 11.1

pCO2 6.6

May 31st

APRV, no ECCMO

25%/4.29 cc/kg

Ppeak 24

Pplat 24

Pmean 21

pH 7.41

pO2 13.8

pCO2 7.0

June 22nd

No mechanical ventilation, no ECMO

2 L O2 nasal canula

n.a

No ABG