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Table 1 Baseline characteristics of 552 patients with PaO2/FiO2 ratios ≤ 300 mm Hg

From: Etiology-associated heterogeneity in acute respiratory distress syndrome: a retrospective cohort study

Characteristics PaO2/FiO2 ≤ 300 mm Hg
ARDS (n = 258) Non-ARDS (n = 294)
Age, year, median (IQR) 67 (55–76) 68 (59–80)
Sex, female, n (%) 83 (32) 106 (36)
Body mass index, median (IQR) 22.8 (20–26) 23.9 (20.7–27.6)
SAPS II score, median (IQR) 49 (40–57) 47 (39–57)
Comorbidities, n (%)
 Cancer 111 (43) 106 (36.1)
 Cardiovascular diseases 58 (22.5) 110 (37.4)
 Chronic obstructive airway diseases 22 (8.5) 34 (11.6)
 Liver cirrhosis 20 (7.8) 19 (6.5)
 Chronic kidney diseases 49 (19) 77 (26.2)
 Diabetes 66 (25.6) 109 (37.1)
 Autoimmune diseases 24 (9.3) 12 (4.1)
Respiratory parameters, median (IQR)
 FiO2 0.63 (0.5–1.0) 0.6 (0.45–0.8)
 PaO2/FiO2 ratio, mm Hg 143 (99–200) 169 (121–226)
 PEEP, cm H2O 8 (6–10) 6 (5–8)
 pH 7.42 (7.37–7.45) 7.41 (7.36–7.45)
 PaCO2, mm Hg 32 (28–37) 34 (29–41)
 HCO3, mmol/L 21 (18–24) 22 (19–25)
 Tidal volume/pBW, mL/kg 8.6 (7.3–10.3) 8.2 (6.8–9.8)
 Minute ventilation, L/min 10.5 (8.2–13.1) 8.3 (6.5–11.2)
 Respiratory compliance, mL/cm H2O 30 (25–40) 30 (23–39)
 Respiratory resistance, cm H2O‧s/L 15 (12–18) 17 (13–20)
Biomarkers, median (IQR)
 C-reactive protein, mg/dL 14.4 (8–20.4) 5.8 (1.8–12.8)
 Platelet, K/μL 140 (72–208) 154 (91–224)
 D-dimer, mg/L 4.5 (2.3–11.8) 7.0 (2.4–27.0)
 Lactate dehydrogenase, U/L 428 (316–734) 368 (215–612)
 Lactic acid, mmol/L 2.3 (1.5–4.2) 2.8 (1.5–5.5)
 Albumin, g/dL 2.7 (2.3–2.9) 2.9 (2.5–3.3)
  1. IQR interquartile range, SAPS simplified acute physiology score