Table 1 Baseline characteristics of 552 patients with PaO2/FiO2 ratios ≤ 300 mm Hg
Characteristics | PaO2/FiO2 ≤ 300 mm Hg | |
|---|---|---|
ARDS (n = 258) | Non-ARDS (n = 294) | |
Age, year, median (IQR) | 67 (55–76) | 68 (59–80) |
Sex, female, n (%) | 83 (32) | 106 (36) |
Body mass index, median (IQR) | 22.8 (20–26) | 23.9 (20.7–27.6) |
SAPS II score, median (IQR) | 49 (40–57) | 47 (39–57) |
Comorbidities, n (%) | ||
 Cancer | 111 (43) | 106 (36.1) |
 Cardiovascular diseases | 58 (22.5) | 110 (37.4) |
 Chronic obstructive airway diseases | 22 (8.5) | 34 (11.6) |
 Liver cirrhosis | 20 (7.8) | 19 (6.5) |
 Chronic kidney diseases | 49 (19) | 77 (26.2) |
 Diabetes | 66 (25.6) | 109 (37.1) |
 Autoimmune diseases | 24 (9.3) | 12 (4.1) |
Respiratory parameters, median (IQR) | ||
 FiO2 | 0.63 (0.5–1.0) | 0.6 (0.45–0.8) |
 PaO2/FiO2 ratio, mm Hg | 143 (99–200) | 169 (121–226) |
 PEEP, cm H2O | 8 (6–10) | 6 (5–8) |
 pH | 7.42 (7.37–7.45) | 7.41 (7.36–7.45) |
 PaCO2, mm Hg | 32 (28–37) | 34 (29–41) |
 HCO3−, mmol/L | 21 (18–24) | 22 (19–25) |
 Tidal volume/pBW, mL/kg | 8.6 (7.3–10.3) | 8.2 (6.8–9.8) |
 Minute ventilation, L/min | 10.5 (8.2–13.1) | 8.3 (6.5–11.2) |
 Respiratory compliance, mL/cm H2O | 30 (25–40) | 30 (23–39) |
 Respiratory resistance, cm H2O‧s/L | 15 (12–18) | 17 (13–20) |
Biomarkers, median (IQR) | ||
 C-reactive protein, mg/dL | 14.4 (8–20.4) | 5.8 (1.8–12.8) |
 Platelet, K/μL | 140 (72–208) | 154 (91–224) |
 D-dimer, mg/L | 4.5 (2.3–11.8) | 7.0 (2.4–27.0) |
 Lactate dehydrogenase, U/L | 428 (316–734) | 368 (215–612) |
 Lactic acid, mmol/L | 2.3 (1.5–4.2) | 2.8 (1.5–5.5) |
 Albumin, g/dL | 2.7 (2.3–2.9) | 2.9 (2.5–3.3) |