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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: Long non-coding RNA CDKN2B-AS1 enhances LPS-induced apoptotic and inflammatory damages in human lung epithelial cells via regulating the miR-140-5p/TGFBR2/Smad3 signal network

Fig. 1

CDKN2B-AS1 and TGFBR2 were overexpressed in sepsis patients. a, b CDKN2B-AS1 (a) and TGFBR2 mRNA (b) levels were examined by qRT-PCR in serum samples of 47 sepsis patients and 55 healthy controls. GAPDH was used as an internal control, and the relative expression in sepsis group was compared to the healthy control group (set as 1). (c) TGFBR2 protein level was detected by ELISA in 47 sepsis patients compared to 55 healthy controls. (d) Pearson’s correlation coefficient was performed for the relation analysis between CDK N2B-AS1 and TGFBR2 in 47 sepsis patients. The number of replicates for each experiment was 3 (n = 3). Student’s t-test was used for statistical analysis. ***P < 0.001

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