Long non-coding RNA CDKN2B-AS1 enhances LPS-induced apoptotic and inflammatory damages in human lung epithelial cells via regulating the miR-140-5p/TGFBR2/Smad3 signal network

Table 2 Characteristics of participants

Items	Healthy controls (n = 55)	Sepsis patients (n = 47)	P value
Age (years), mean ± SD	53.1 ± 5.3	54.3 ± 7.2	0.336
Sex, no. (%)			0.379
Female	21(38%)	22(47%)
Male	34(62%)	25(53%)
Smoke, no (%)	19(35%)	21(45%)	0.296
Drink, no (%)	26(47%)	23(49%)	0.867
Scr (mg/dL)	0.8 ± 0.2	1.5 ± 0.4	< 0.001
CRP (mg/L)	3.3 ± 1.9	94.3 ± 42.7	< 0.001
Albumin (g/L)	41.2 ± 3.8	23.5 ± 4.1	< 0.001
WBC (*10⁹ /L)	5.5 ± 1.3	18.6 ± 8.9	< 0.001
APACHE II score	–	12.6 ± 3.5

SD, standard deviation; Scr, serum creatinine; CRP, C-reactive protein; WBC, white blood cell; APACHE II, acute physiology and chronic health evaluation II

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