Table 1 Clinical characteristics on admission to the weaning center— comparison of patients with weaning success and weaning failure

Age (years)

69 (60–76)

68 (59–76)

70 (63–75)

0.609^c

Gender (male)

82 (63.1)

59 (68.8)

23 (52.3)

0.069^d

Body mass index (kg/m²)

27.9 (± 6.9)

27.3 (± 6.6)

29.1 (± 7.4)

0.369^c

 Obesity (BMI ≥ 30 kg/m²)

40 (30.8)

24 (27.9)

16 (36.4)

0.325^d

Smoking history

48 (36.9)

21 (24.5)

27 (61.4)

 < 0.001^d

APACHE-II (points)

15.9 (± 5.3)

15.8 (± 5.3)

15.9 (± 5.4)

0.905^b

Albumin (g/dL)

2.2 (± 0.5)

2.2 (± 0.6)

2.2 (± 0.5)

0.338^c

Ventilator days on admission

25 (16–34)

27 (17–35)

23 (16–30)

0.123^c

Time from Intubation to tracheostomy (days)

12 (7–18)

13 (7–19)

10 (6–15)

0.057^c

ECLA

14 (10.8)

13 (15.1)

1 (2.3)

0.026^d

Reason for mechanical ventilation

Pneumonia

51 (39.2)

31 (36.0)

20 (45.5)

0.300^d

 SARS-CoV-2 infection

4 (3.1)

4 (4.7)

0 (0.0)

–

Surgery

32 (24.6)

25 (29.1)

7 (15.9)

0.101^d

Cardiopulmonary resuscitation

10 (7.7)

8 (9.3)

2 (4.5)

0.337^d

Acute exacerbation of COPD

10 (7.7)

2 (2.3)

8 (18.2)

0.001^d

Acute heart failure

6 (4.6)

5 (5.8)

1 (2.3)

0.663^e

Sepsis (including septic shock)

7 (5.4)

5 (5.8)

2 (4.5)

1.000^e

Other

17 (13.1)

10 (11.6)

7 (15.9)

0.495^d

Comorbidities

Charlson comorbidity index (points)

5.5 (± 2.3)

5.4 (± 2.4)

5.6 (± 2.1)

0.611^c

Renal insufficiency

46 (35.4)

36 (41.9)

10 (22.7)

0.032^d

 Hemodialysis

24 (18.5)

21 (24.4)

3 (6.8)

0.289^d

Diabetes mellitus

35 (26.9)

20 (23.3)

15 (34.1)

0.189^d

Coronary artery disease

33 (25.4)

23 (26.7)

10 (22.7)

0.620^d

COPD

30 (23.1)

5 (5.8)

25 (56.8)

 < 0.001^d

Chronic heart failure

17 (13.1)

14 (16.3)

3 (6.8)

0.132^d

Malignancy

10 (7.7)

7 (8.1)

3 (6.8)

0.790^d

Hepatopathy

7 (5.4)

5 (5.8)

2 (4.5)

1.000^e

Interstitial lung disease

8 (6.2)

6 (7.0)

2 (4.5)

0.716^e