Fig. 1

LINC01089 expression is markedly down-regulated in LUAD cells and LINC01089 overexpression suppresses LUAD cell proliferation and migration. a RT-qPCR was adopted to detect the LINC01089 expression in LUAD cell lines and BEAS-2B cell. b Overexpression efficiency of LINC01089 was detected via RT-qPCR in A549 and H-1975 cells. c, d Cell proliferation ability of A549 and H-1975 cells was measured through CCK-8 and EdU assays after cells were transfected with pcDNA3.1/LINC01089. e The apoptosis ability of pcDNA3.1/LINC01089-transfected cells was tested via flow cytometry analysis. f, g Transwell and wound healing assays were utilized to detect cell migration capability. The statistical analysis of Fig. 1a was assessed with one-way ANOVA. The statistical analysis of Fig. 1b, d, e, f and g was evaluated with Student’s t test. The statistical analysis of Fig. 1C was tested with two-way ANOVA. **P < 0.01